Search for dissertations about: "Bioenergetic state"

Found 5 swedish dissertations containing the words Bioenergetic state.

2. 1. On bioenergetic failure in septic shock : lactate kinetics and mitochondrial respiration

   Author : Jonathan Grip; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Septic shock, a dysregulated immune response to an infection, is a major cause of mortality and morbidity in patients treated in intensive care units (ICUs). The cause of the organ dysfunction seen in sepsis is still not fully elucidated, but a disrupted intracellular metabolism, a bioenergetics failure, has been suggested as a possible mechanism. READ MORE

4. 2. Numerical optimization of pacing strategies in locomotive endurance sports

   Author : David Sundström; Mats Tinnsten; Peter Carlsson; Mikael Bäckström; Erik Bruun Simonsen; Mittuniversitetet; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Pacing strategy; optimization; numerical simulation; equations of motion; method of moving asymptotes; cross-country skiing; cycling; Farthållningsstrategi; optimering; numerisk simulering; rörelseekvationer; method of moving asymptotes; längdskidåkning; cykling;

   Abstract : This thesis is devoted to the optimization of pacing strategies in two locomotive endurance sports; cross-country skiing and road cycling. It has been established that constant pace and variable power distributions are optimal if purely mechanical aspects of locomotion are considered in these sports. READ MORE

5. 3. Mitochondrial permeability transition following calcium overload. - Its role in neuronal cell death and potential as a pharmacological target

   Author : Magnus Hansson; Sektion IV; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; farmakognosi; farmaci; Bioenergetik; Bioenergetics; neuropsykologi; toxikologi; neurofysiologi; Neurologi; Neurology; neurophysiology; neuropsychology; Neurodegeneration; Mitochondria; Brain; Pharmacological sciences; pharmacognosy; pharmacy; Farmakologi; toxicology;

   Abstract : There is currently no clinically available drug with neuroprotective properties to limit the evolving cell death following e.g. stroke or traumatic brain injury. The mitochondrial permeability transition (mPT) is a potential pathological mechanism causing cell death in the CNS. READ MORE

6. 4. On ischemia/reperfusion injury and rejection in concordant xenotransplantation to the rat

   Author : Daniel Jan Lukes; Göteborgs universitet; []
   Keywords : Concordant; xenotransplantation; rat; hamster; mouse; rejection; necrosis; PCr; ß-ATP; ROS; SOE light; I RP; IPC;

   Abstract : Studies in concordant (without preformed antibodies) rodent xenotransplantation (transplantation between species) models have focused, to date, on immunological disparities. In allotransplantation (transplantation within species), there is evidence suggesting that early ischemic events may contribute to later rejection episodes and to the development of chronicrejection features. READ MORE

7. 5. Biomarkers for assessing benthic pollution impacts in a subtropical estuary, Mozambique

   Author : Maria Perpétua Janeiro Scarlet; Göteborgs universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; subtrophical estuary; contaminants; biological hierarcial biomarkers; scope for growth; burrowing response; acethylcholinesterase; benthic fauna; southern Mozambique;

   Abstract : This thesis focuses on the marine environment in a subtropical estuary and particularly on exploring a suite of easy-to-use, cost effective and environmentally valid biological response tools (biomarkers). The main driving force of the thesis is the knowledge of the numerous anthropogenic impacts. READ MORE