Search for dissertations about: "Biofysik"

Showing result 11 - 15 of 682 swedish dissertations containing the word Biofysik.

  2. 11. The choreography of protein vibrations : Improved methods of observing and simulating the infrared absorption of proteins

    Author : Eeva-Liisa Karjalainen; Andreas Barth; Astrid Gräslund; Timothy A. Keiderling; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Infrared spectroscopy; FTIR; protein; atpase; amyloid; caged compound; amide I; transition dipole coupling; exciton theory; simulation; Molecular biophysics; Molekylär biofysik; Biophysics; biofysik;

    Abstract : The work presented in this thesis has striven toward improving the capability to study proteins using infrared (IR) spectroscopy. This includes development of new and improved experimental and theoretical methods to selectively observe and simulate protein vibrations. READ MORE

  4. 12. NMR Investigations of Peptide-Membrane Interactions, Modulation of Peptide-Lipid Interaction as a Switch in Signaling across the Lipid Bilayer

    Author : Sofia Unnerståle; Lena Mäler; Göran Widmalm; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; peptide-lipid interaction; membrane mimetic; NMR; biophysics; Molecular biophysics; Molekylär biofysik; biofysik; Biophysics;

    Abstract : The complexity of multi cellular organisms demands systems that facilitate communicationbetween cells. The neurons in our brains for instance are specialized in this cell-cellcommunication. READ MORE

  5. 13. Biophysical investigations of ribonucleotide reductase : Activation and inhibition mechanisms

    Author : Maria Öhrström; Astrid Gräslund; Anders Hofer; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biophysics; Molekylär biofysik; Biophysics; biofysik;

    Abstract : Ribonucleotide reductase (RNR) is the enzyme responsible for de novo synthesis of deoxyribonucleotides, needed for both synthesis and repair of cellular DNA. The RNRs known so far are divided into three distinct classes; I, II and III. The conventional class I enzyme is composed of two separate subunits. READ MORE

  6. 14. The Biophysics of Na+,K+-ATPase in neuronal health and disease

    Author : Evgeny E. Akkuratov; Hjalmar Brismar; Anita Aperia; Stefan Wennmalm; Poul Nissen; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Na ; K -ATPase; NMDA receptor; ouabain; phosphoproteome; oligomerization; rapid-onset dystonia-parkinsonism; Biologisk fysik; Biological Physics;

    Abstract : Na+,K+-ATPase is one of the most important proteins in the mammalian cell. It creates sodium and potassium gradients which are fundamental for the membrane potential and sodium-dependent secondary active transport. READ MORE

  7. 15. Automating STED microscopy for functional and structural live-cell imaging

    Author : Jonatan Alvelid; Ilaria Testa; Eggeling Christian; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; STED; microscopy; nanoscopy; super-resolution microscopy; automation; image analysis; fluorophores; Biologisk fysik; Biological Physics;

    Abstract : Optical microscopy imaging methods are today invaluable tools for studies in life sciences as they allow visualization of biological systems, tissues, cells, and sub-cellular compartments from millimetres down to nanometres. The invention and development of nanoscopy in the past 20 years has pushed fluorescence microscopy down to the nanoscale, reaching beyond the natural diffraction limit of light that does not allow focusing of visible light below sizes of around 200 nm, and into the realm of what was previously only thought possible with electron microscopy. READ MORE