Search for dissertations about: "Bioinformatics"

Showing result 21 - 25 of 635 swedish dissertations containing the word Bioinformatics.

  1. 21. Fusing Domain Knowledge with Data : Applications in Bioinformatics

    Author : Claes Andersson; Jan Komorowski; Mats Gustafsson; Yves Moreau; Uppsala universitet; []
    Keywords : Bioinformatics; cell cycle; cancer chemotherapy; predictive tests; performance estimation; bioinformatics; Bioinformatik;

    Abstract : Massively parallel measurement techniques can be used for generating hypotheses about the molecular underpinnings of a biological systems. This thesis investigates how domain knowledge can be fused to data from different sources in order to generate more sophisticated hypotheses and improved analyses. READ MORE

  2. 22. The labyrinth of protein classification: a pipeline forselection and classification of biological data

    Author : Benedetta Pelosi; Neus Visa; Antonio Barragan; Stefan Jansson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; pipeline; filtering; machine learning; deep learning; computational biology; bioinformatics; mitochondrial metabolism; carotenoid biosynthesis; orthologs; protein analyses; statistics; biokemi med inriktning mot bioinformatik; Biochemistry towards Bioinformatics; statistik; Statistics;

    Abstract : Recent progress in fundamental biological sciences and medicine has considerably increased the quantity ofdata that can be studied and processed. The main limitation now is not retrieving data, but rather extractinguseful biological insights from the large datasets accumulated. READ MORE

  3. 23. Predicting the route: from protein sequence to sorting in eukaryotic cell

    Author : Marco Salvatore; Arne Elofsson; Norman Davey; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; eukaryotic cell; sorting signals; subcellular localisation; machine learning; biological sequence analysis; bioinformatics; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Abstract : Proteins need to be localised in the correct compartment of a eukaryotic cell to function correctly. Therefore, a protein needs to be transported to the right location. Specific signals present in the protein sequence direct proteins to different subcellular localisations. READ MORE

  4. 24. Development of Molecular Biology and Bioinformatics Tools : From Hydrogen Evolution to Cell Division in Cyanobacteria

    Author : Fernando Lopes Pinto; Peter Lindblad; Röbbe Wünschiers; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cyanobacteria; hydrogen; RNA; bioinformatics; RT-PCR; RACE; transcription; Molecular biology; Molekylärbiologi; Bioinformatics; Bioinformatik; Molecular Biology; Molekylärbiologi;

    Abstract : The use of fossil fuels presents a particularly interesting challenge - our society strongly depends on coal and oil, but we are aware that their use is damaging the environment. Currently, this awareness is gaining momentum, and pressure to evolve towards an energetically cleaner planet is very strong. READ MORE

  5. 25. Analysis of RNA and DNA sequencing data : Improved bioinformatics applications

    Author : Benjamín Sigurgeirsson; Joakim Lundeberg; Simon Anders; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; RNA sequencing; exome sequencing; bioinformatics; gene expression; differential expression; variant calling; Bioteknologi; Biotechnology;

    Abstract : Massively parallel sequencing has rapidly revolutionized DNA and RNA research. Sample preparations are steadfastly advancing, sequencing costs have plummeted and throughput is ever growing. This progress has resulted in exponential growth in data generation with a corresponding demand for bioinformatic solutions. READ MORE