Search for dissertations about: "Biokemi och Strukturbiologi"

Showing result 11 - 15 of 218 swedish dissertations containing the words Biokemi och Strukturbiologi.

  2. 11. Role of respiratory supercomplexes : Electronic connection between complexes III and IV

    Author : Agnes Moe; Peter Brzezinski; James A. Letts; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; electron transfer; cytochrome c oxidase; cytochrome bc1; respiratory supercomplex; bioenergetics; membrane protein; biokemi; Biochemistry;

    Abstract : In the final step of cellular respiration, electrons are transferred through the respiratory chain to reduce molecular oxygen to water. The energy released in this chain is used to maintain a proton electrochemical gradient across the cell membrane, which is used, for example, by the ATP synthase to produce ATP. READ MORE

  4. 12. Structural characterisation of mitochondrial macromolecular complexes using cryo-EM : Mitoribosome biogenesis and respiratory chain supercomplex

    Author : Sorbhi Rathore; Martin Ott; Daniel Wilson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mitochondria; mitoribosome biogenesis; mitoribosome assembly factors; yeast respiratory supercomplexes; single particle electron cryo-microscopy; cryo-EM sample preparation; Biochemistry; biokemi;

    Abstract : Mitochondria, popularly known as powerhouse of the cell, contain specialised mitoribosomes that synthesise essential membrane proteins. These essential proteins are required to form enzyme complexes, which carry out the process of oxidative phosphorylation (OXPHOS). READ MORE

  5. 13. Structural transitions of proton-gated ion channels : Involving pH sensing, heterogeneity and lipid interactions

    Author : Urška Rovšnik; Erik Lindahl; Hugues Nury; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ion channels; cryo-electron microscopy; pH gating; simulations; structure-function relationship; GLIC; DeCLIC; biokemi; Biochemistry;

    Abstract : Studying protein structure and function involves analyzing the relationship between a protein's three-dimensional assembly and its dynamic biochemical activity. The superfamily of pentameric ligand-gated ion channels (pLGICs) constitutes a classic yet illuminating experimental system for structure-function studies. READ MORE

  6. 14. Prokaryotic respiratory supercomplexes : Studies of interactions between complexes III and IV

    Author : Olga Stah; Pia Ädelroth; Petra Hellwig; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; bioenergetics; membrane protein; bacterial respiration; electron transport chain; supercomplex; cytochrome c oxidase; membrane-anchored cytochrome c; cytochrome bc1 complex; electron transfer; proton transfer; time-resolved spectroscopy; apoptosis; biokemi; Biochemistry;

    Abstract : Respiratory processes for cellular energy conversion are carried out by the membrane-associated enzymes of the electron transfer chain (ETC). In recent years there has been emerging data showing that the members of the ETC organize into higher-level assemblies called supercomplexes (SCs) whose functional relevance is not yet fully understood. READ MORE

  7. 15. Establishing the molecular mechanism of sodium/proton exchangers

    Author : Povilas Uzdavinys; David Drew; Peter Brzezinski; M.D. Daniel Fuster; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; membrane protein; secondary active transporters; sodium proton exchangers; proton transport; structure; energetics; Biochemistry; biokemi;

    Abstract : Sodium/proton exchangers are ubiquitous secondary active transporters that can be found in all kingdoms of life. These proteins facilitate the transport of protons in exchange for sodium ions to help regulate internal pH, sodium levels, and cell volume. READ MORE