Search for dissertations about: "Biologi med inriktning mot ekotoxikologi"

Showing result 1 - 5 of 9 swedish dissertations containing the words Biologi med inriktning mot ekotoxikologi.

  1. 1. Pheromonal Mediated Behaviour and Endocrine Responses in Salmonids The impact of Cypermethrin, Copper, and Glyphosate

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Alia Jaensson; Södertörns högskola.; Södertörns högskola.; Uppsala universitet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURAL SCIENCES Biology Cell and molecular biology Toxicology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Toxikologi; Biologi med inriktning mot ekotoxikologi; Biology with specialization in Environmental Toxicology; Cypermethrin; copper; glyphosate; behaviour; hormones; pheromones; olfaction; 11-ketotestosterone 11-KT ; 17α; 20β-dihydroxy-4-pregnen-3-one 17; 20β-P ; reproduction;

    Abstract : The effects of cypermethrin, copper and glyphosate on the endocrine system and subsequent response to female pheromones were investigated in mature male brown trout (Salmo trutta) parr.  Responses measured were the amount of strippable milt, blood plasma levels of both an androgen (11-ketotestosterone (11-KT)) and a progestin (17α,20β-dihydroxy-4-pregnen-3-one (17,20b-P)), and behavioural changes. READ MORE

  2. 2. In Vitro Studies of Adrenocorticolytic DDT Metabolites, with Special Focus on 3-methylsulfonyl-DDE

    University dissertation from Uppsala, Sweden : Acta Universitatis Upsaliensis

    Author : Vendela Asp; Uppsala universitet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Toxicity; 3-methylsulfonyl-DDE; CYP; adrenal cortex; metabolic activation; steroid hormones; Y-1; H295R; mitotane; adrenocortical carcinoma; NATURAL SCIENCES Biology Cell and molecular biology Toxicology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Toxikologi; Biologi med inriktning mot ekotoxikologi; Biology with specialization in Environmental Toxicology;

    Abstract : The DDT metabolite 3-methylsulfonyl-DDE (3-MeSO2-DDE) is bioactivated by cytochrome P450 11B1 (CYP11B1) in the adrenal cortex of mice and forms irreversibly bound protein adducts, reduces glucocorticoid secretion, and induces cell death selectively in cortisol-producing adrenocortical cells. 3-MeSO2-DDE has therefore been proposed as a lead compound for an improved adrenocortical carcinoma (ACC) therapy. READ MORE

  3. 3. Progestagenic Aquatic Contaminants Act as Potent Androgens in Fish Experimental Studies in Three-spined Stickleback and Zebrafish

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Johan Svensson; Uppsala universitet.; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Pharmaceuticals as contaminants; Progestins; Androgenic properties; Fish; Biologi med inriktning mot ekotoxikologi; Biology with specialization in Environmental Toxicology;

    Abstract : The extensive use of pharmaceuticals and their poor removal by wastewater treatment plants has led to the emergence of pharmaceutical compounds as global aquatic contaminants. Progestins, the synthetic analogues to progesterone (P4), are receiving increasing attention as contaminants and have been shown to impair reproduction in fish and amphibians at low ng L-1 concentrations. READ MORE

  4. 4. Cellular transport and secretion of the cyanobacterial neurotoxin BMAA into milk and egg Implications for developmental neurotoxicity

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Marie Andersson; Uppsala universitet.; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; BMAA; beta-N-methylamino-L-alanine; milk; secretion; amino acid transporter; autoradiography; metabolism; Biologi med inriktning mot ekotoxikologi; Biology with specialization in Environmental Toxicology;

    Abstract : The cyanobacterial amino acid β-N-methylamino-L-alanine (BMAA) is a neurotoxin implicated in the etiology of neurodegenerative diseases. Cyanobacteria are cosmopolitan organisms present in various environments. READ MORE

  5. 5. Azoles and Contaminants in Treated Effluents Interact with CYP1 and CYP19 in Fish

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Kristina Beijer; Uppsala universitet.; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Azole; fungicide; chemical; CYP1A; CYP19; EROD; aromatase; effluent; STP; wastewater; fish; stickleback; rainbow trout; Biologi med inriktning mot ekotoxikologi; Biology with specialization in Environmental Toxicology;

    Abstract : Numerous contaminants are present in mixtures in the aquatic environment. Among these are the azoles, a group of chemicals that includes both pharmaceuticals and pesticides. Azole fungicides are designed to inhibit lanosterol 14-demethylase (cytochrome P450 (CYP) 51), while other azoles are intended to inhibit aromatase (CYP19), i.e. READ MORE