Search for dissertations about: "Biologi med inriktning mot molekylär bioteknik"

Showing result 1 - 5 of 24 swedish dissertations containing the words Biologi med inriktning mot molekylär bioteknik.

  2. 1. Adenovirus for Cancer Therapy : With a Focus on its Surface Modification

    Author : Di Yu; Magnus Essand; Dirk Nettelbeck; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; Adenovirus; cancer; therapy; neuroblastoma; neuroendocrine; modification; Tat; PTD; cell penetrating peptide; Helicobacter pylori; NAP; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Klinisk virologi; Clinical Virology; Medical Virology; Medicinsk virologi; Molekylär medicin; Molecular Medicine; Molekylär bioteknik; Molecular Biotechnology;

    Abstract : Adenovirus serotype 5 (Ad5) is widely used as an oncolytic agent for cancer therapy. However, its infectivity is highly dependent on the expression level of coxsackievirus-adenovirus receptor (CAR) on the surface of tumor cells. READ MORE

  4. 2. Modelling Approaches to Molecular Systems Biology

    Author : David Fange; Måns Ehrenberg; Johan Elf; Terence Hwa; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; stochastic reaction-diffuion kinetics; antibiotic drugs; efflux pumps; amino acid biosynthesis; Min-system; rRNA operon; transcription; Molecular biology; Molekylärbiologi; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Abstract : Implementation and analysis of mathematical models can serve as a powerful tool in understanding how intracellular processes in bacteria affect the bacterial phenotype. In this thesis I have implemented and analysed models of a number of different parts of the bacterium E. coli in order to understand these types of connections. READ MORE

  5. 3. DNA-Assisted Immunoassays for High-Performance Protein Analyses

    Author : Junhong Yan; Masood Kamali-Moghaddam; Ulf Landegren; Christer Wingren; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; MEDICAL AND HEALTH SCIENCES; proximity ligation assay; magnetic beads; conjugation; phosphorylation; affinity binder; protein complexes; recombinant binder; sensitivity; specificity; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Abstract : Proteins play important roles in most cellular functions, such as, replication, transcription regulation, signal transduction, for catalyzing chemical reaction, etc. Technologies developed to identify proteins rely either on observing their own properties such as charge, size, mass to charge ratio or sequence composition; or on using affinity reagents that recognize specific protein targets. READ MORE

  6. 4. Calculations of Reaction Mechanisms and Entropic Effects in Enzyme Catalysis

    Author : Masoud Kazemi; Johan Åqvist; Per E. M. Siegbahn; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES; Enzyme catalysis; Entropy; Cytidine deamination; Ribosome; Peptidyl-tRNA hydrolysis; Peptide bond formation; Empirical valence bond method; Density functional theory; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi; Biokemi; Biochemistry; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Abstract : Ground state destabilization is a hypothesis to explain enzyme catalysis. The most popular interpretation of it is the entropic effect, which states that enzymes accelerate biochemical reactions by bringing the reactants to a favorable position and orientation and the entropy cost of this is compensated by enthalpy of binding. READ MORE

  7. 5. Mechanisms and Inhibition of EF-G-dependent Translocation and Recycling of the Bacterial Ribosome

    Author : Anneli Borg; Måns Ehrenberg; Ruben Gonzalez; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Protein synthesis; Elongation factor G; Translocation; Ribosome recycling; Fusidic acid; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Abstract : The GTPase elongation factor G (EF-G) is an important player in the complex process of protein synthesis by bacterial ribosomes. Although extensively studied much remains to be learned about this fascinating protein. READ MORE