Search for dissertations about: "Biologi med inriktning mot molekylär bioteknik"

Showing result 6 - 10 of 17 swedish dissertations containing the words Biologi med inriktning mot molekylär bioteknik.

  1. 6. Modelling Approaches to Molecular Systems Biology

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : David Fange; Uppsala universitet.; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; stochastic reaction-diffuion kinetics; antibiotic drugs; efflux pumps; amino acid biosynthesis; Min-system; rRNA operon; transcription; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Abstract : Implementation and analysis of mathematical models can serve as a powerful tool in understanding how intracellular processes in bacteria affect the bacterial phenotype. In this thesis I have implemented and analysed models of a number of different parts of the bacterium E. coli in order to understand these types of connections. READ MORE

  2. 7. Solid-phase Proximity Ligation Assays High-performance and multiplex protein analyses

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Spyros Darmanis; Uppsala universitet.; [2011]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; proximity ligation assay; multiplexed; biomarkers; solid-phase; microparticles; cancer; sequencing; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Abstract : Protein biomarkers circulating in blood hold the promise of improved diagnosis, prognosis and follow-up of treatment of disease via minimally invasive procedures. For the discovery and validation of such biomarkers, methods are needed that can facilitate parallel, highly specific and in-depth analysis of the blood proteome. READ MORE

  3. 8. Mechanisms and Inhibition of EF-G-dependent Translocation and Recycling of the Bacterial Ribosome

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Anneli Borg; Uppsala universitet.; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein synthesis; Elongation factor G; Translocation; Ribosome recycling; Fusidic acid; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Abstract : The GTPase elongation factor G (EF-G) is an important player in the complex process of protein synthesis by bacterial ribosomes. Although extensively studied much remains to be learned about this fascinating protein. READ MORE

  4. 9. Proximity Ligation Assay for High Performance Protein Analysis in Medicine

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Gucci Jijuan Gu; Uppsala universitet.; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein; post-translational modification; interactions; protein domain; western blotting; MARK; tau; AD; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Abstract : High quality reagents are preconditions for high performance protein analyses. But despite progress in some techniques, e.g. mass spectrometry, there is still a lack of affinity-based detection techniques with enhanced precision, specificity, and sensitivity. READ MORE

  5. 10. Rate and Accuracy of Bacterial Protein Synthesis

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Magnus Johansson; Uppsala universitet.; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein synthesis; ribosome; peptidyl transfer; rate-accuracy trade-off; kinetics; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Abstract : High levels of accuracy in transcription, aminoacylation of tRNA, and mRNA translation are essential for all life forms. However, high accuracy also necessarily means large energy dissipation and slow kinetics. Therefore, in vivo there is a fine tuned balance between rate and accuracy of key chemical reactions. READ MORE