Search for dissertations about: "Biologi med inriktning mot molekylär immunologi"

Showing result 6 - 10 of 12 swedish dissertations containing the words Biologi med inriktning mot molekylär immunologi.

  2. 6. Transcriptional and morphological analysis of organ donor pancreata

    Author : Anton Stenwall; Oskar Skog; Lena Eliasson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pancreas; Diabetes; Islet of Langerhans; Beta-cell; Immunology; Inflammation; Ageing; Biology with specialization in Molecular Immunology; Biologi med inriktning mot molekylär immunologi;

    Abstract : The diabetes disease panorama affects more than 400 million people world wide – a number projected to rise above 640 million in the next 20 years. Type 1 and type 2 diabetes are associated with adverse complications, resulting in severe morbidity and high healthcare costs exerting substantial strain on society. READ MORE

  4. 7. Cancer Immunotherapy : Evolving Oncolytic viruses and CAR T-cells

    Author : Mohanraj Ramachandran; Magnus Essand; Di Yu; Justyna Leja-Jarblad; Richard Vile; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncolytic virus; Adenovirus; Semliki Forest virus; Cancer immunology; Chimeric antigen receptor T-cells; Immunologi; Immunology; Oncology; Onkologi; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Abstract : In the last decade cancer immunotherapy has taken huge strides forward from bench to bedside and being approved as drugs. Cancer immunotherapy harnesses the power of patient’s own immune system to fight cancer. READ MORE

  5. 8. Mechanisms in Tendon Healing : Pain, Biomarkers and the Role of Mast Cells

    Author : Abdul Alim; Magnus Peterson; Gunnar Pejler; Per Kristiansson; Paul W. Ackermann; Gustav Andersson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tendon Healing; Pain; Biomarkers; Mast Cells; Inflammation; Microdialysis; Neurotransmitters; Glutamate Receptors; Procollagen; Transcriptional factors; Biology with specialization in Molecular Immunology; Biologi med inriktning mot molekylär immunologi; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Neuroscience; Neurovetenskap;

    Abstract : Tendon injuries and tendinopathy are common disorders, but the underlying mechanisms are not well understood. The overall aim of this thesis was to better understand the mechanisms underlying tendon healing, pain, and inflammation. READ MORE

  6. 9. Molecular Genetic and DNA Methylation Profiling of Chronic Lymphocytic Leukaemia : A Focus on Divergent Prognostic Subgroups and Subsets

    Author : Nicola Cahill; Richard Rosenquist; Larry Mansouri; Fergus Ryan; Denis Alexander; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DNA methylation; Chronic lymphocytic leukemia; SNP; array; IGHV3-21; IGHV4-34; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Genetics; Genetik; Medical Genetics; Medicinsk genetik; Molecular Biology; Molekylärbiologi; Molekylär genetik; Molecular Genetics; Oncology; Onkologi;

    Abstract : Advancements in prognostication have improved the subdivision of chronic lymphocytic leukaemia (CLL) into diverse prognostic subgroups. In CLL, IGHV unmutated and IGHV3-21 genes are associated with a poor-prognosis, conversely, IGHV mutated genes with a favourable outcome. READ MORE

  7. 10. Cellular and molecular roles for CDC42 in angiogenesis

    Author : Marco Castro; Christer Betsholtz; Bàrbara Laviña; Rui Benedito; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CDC42; angiogenesis; endothelial cell; vascular malformation; Biology with specialization in Molecular Cell Biology; Biologi med inriktning mot molekylär cellbiologi;

    Abstract : Angiogenesis is the physiological process by which new blood vessels grow and critically depends on the interplay between the major vascular units: endothelial cells, pericytes and smooth muscle cells. Dysfunction and mispatterning of blood vessels are associated with the progression of many vascular complications, and therefore, understanding the causes of vascular dysmorphia is a central question in vascular biology. READ MORE