Search for dissertations about: "Biologi med inriktning mot strukturbiologi"
Showing result 1 - 5 of 23 swedish dissertations containing the words Biologi med inriktning mot strukturbiologi.
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1. Exploring the Molecular Dynamics of Proteins and Viruses
Abstract : Knowledge about structure and dynamics of the important biological macromolecules — proteins, nucleic acids, lipids and sugars — helps to understand their function. Atomic-resolution structures of macromolecules are routinely captured with X-ray crystallography and other techniques. READ MORE
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2. Of spiders, bugs, and men : Structural and functional studies of proteins involved in assembly
Abstract : Protein assembly enables complex machineries while being economical with genetic information. However, protein assembly also constitutes a potential threat to the host, and needs to be carefully regulated.Sulfate is a common source of sulfur for cysteine synthesis in bacteria. READ MORE
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3. Evolutionary and Pharmacological Studies of NPY and QRFP Receptors
Abstract : The neuropeptide Y (NPY) system consists of 3-4 peptides and 4-7 receptors in vertebrates. It has powerful effects on appetite regulation and is involved in many other biological processes including blood pressure regulation, bone formation and anxiety. READ MORE
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4. Antibiotic Resistance and the Cellular Currency S-adenosyl-methionine : Modification of aminoglycosides and nucleic acids
Abstract : Streptomycin and spectinomycin are antibiotics that bind to ribosomes and inhibit protein synthesis. Common resistance mechanisms involve enzymatic modification of the two drugs by aminoglycoside nucleotidyltransferases (ANTs). The first part of this thesis covers the structural mechanism of two ANT enzymes. READ MORE
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5. Structural and Biochemical Characterizations of Three Potential Drug Targets from Pathogens
Abstract : As antibiotic resistance of various pathogens emerged globally, the need for new effective drugs with novel modes of action became urgent. In this thesis, we focus on infectious diseases, e.g. READ MORE