Search for dissertations about: "Biological Markers: analysis"

Showing result 16 - 20 of 184 swedish dissertations containing the words Biological Markers: analysis.

  2. 16. Genetic Mapping of Susceptibility Genes for Systemic Lupus Erythematosus

    Author : Bo Johanneson; Jean Pierre Hugot; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; Association analysis; Candidate gene; Complex disease; Genome scan; Linkage analysis; Mapping; Susceptibility genes; Systemic lupus erythematosus; Genetik; Genetics; Genetik; medicinsk genetik; Medical Genetics;

    Abstract : Systemic lupus erythematosus (SLE) is a complex autoimmune disease with unknown etiology. The aim of this thesis was to identify susceptibility regions through genetic mapping, using model-based linkage analysis on nuclear and extended SLE multicase families. READ MORE

  4. 17. Biomarkers aiming at cancer risk estimation of polycyclic aromatic hydrocarbons

    Author : Hans Helleberg; Kimmo Peltonen; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Physical Biology; fysikalisk biologi;

    Abstract : Polycyclic aromatic hydrocarbons (PAH), a family of compounds that are formed in incomplete combustion of organic matter, occur as general pollutants in air and food. Exposure to PAH is, according to preliminary estimates, associated with non-acceptable cancer risks showing the need for improved data to be used in risk estimation. READ MORE

  5. 18. Genome mapping of the horse

    Author : Gabriella Lindgren; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Horse; microsatellites; linkage analysis; FISH; Type I markers; BAc library; Y chromosome; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; Evolutionary Genetics; evolutionär genetik;

    Abstract : Our ability to map and sequence whole genomes is one of the most important developments in biological science. It will provide us with an unprecedented insight into the genetic background of phenotypic traits, such as disease resistance, reproduction and growth and also makes it feasible to study the processes of genome evolution. READ MORE

  6. 19. Mitochondrial Genome Analysis Using Next Generation Sequencing for Forensic Applications

    Author : Kimberly Sturk-Andreaggi; Marie Allen; Antti Sajantila; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mitochondrial DNA; next generation sequencing; massively parallel sequencing; forensic genetics; nuclear mitochondrial DNA segment NUMT ; length heteroplasmy; haplogroup; quality control; population data; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Abstract : Mitochondrial DNA (mtDNA) analysis plays a specialized role in forensic applications, overcoming certain limitations of autosomal DNA markers. The high copy number and uniparental inheritance pattern of mtDNA are advantageous in cases involving shed hairs and aged skeletal elements, especially decades-old missing persons cases. READ MORE

  7. 20. Assesing performance of PCR analysis using Bayesian modelling

    Author : Ronny Hedell; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Bayesian; Hierarchical model; PCR; Low-template DNA; Bacillus anthracis; Sensitivity; Forensic science; Forensic science;

    Abstract : Different analytical methods are available to analyse the DNA samples from crime scenes or to screen samples for the presence of some target bacterium. For this purpose a method known as Polymerase Chain Reaction (PCR) can often be used. READ MORE