Search for dissertations about: "Biological Markers: analysis"

Showing result 6 - 10 of 184 swedish dissertations containing the words Biological Markers: analysis.

  1. 6. Two Optimization Problems in Genetics : Multi-dimensional QTL Analysis and Haplotype Inference

    Author : Carl Nettelblad; Sverker Holmgren; José M. Álvarez-Castro; Jukka Corander; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; quantitative trait loci; genome-wide association studies; hidden Markov models; numerical optimization; linkage analysis; haplotype inference; genotype imputation; high performance computing;

    Abstract : The existence of new technologies, implemented in efficient platforms and workflows has made massive genotyping available to all fields of biology and medicine. Genetic analyses are no longer dominated by experimental work in laboratories, but rather the interpretation of the resulting data. READ MORE

  2. 7. Characterization and Use of a Multiplex PCR-based System: Random amplified Polymorphic DNA

    Author : Christer Halldén; Malmö Klinisk kemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; DNA mixtures; competition; graphical genotypes; bulked segregant analysis; linkage map; genetic distance; RFLP markers; RAPD markers; oilseed rape; sugar beet; Genetics; cytogenetics; Genetik; cytogenetik;

    Abstract : Random amplified polymorhic DNA (RAPD) is a PCR-based marker system that makes use of universal sets of short oligonucleotides that amplify random DNA fragments under low-stringency conditions. The RAPD marker system has found widespread use and possesses a number of very positive features, being a multiplex and universal system. READ MORE

  3. 8. Assessment of Novel Molecular Prognostic Markers in Chronic Lymphocytic Leukemia

    Author : Mohamed Arifin Bin Kaderi; Richard Rosenquist Rosenquist; Mahmoud Mansouri; Mattias Jansson; Denis Alexander; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chronic lymphocytic leukemia; prognostic markers; single nucleotide polymorphisms; RNA-based markers; Medical genetics; Medicinsk genetik; Genetics; Genetik; Clinical genetics; Klinisk genetik; Medical laboratory science; Medicinsk laboratorievetenskap; Oncology; Onkologi; Haematology; Hematologi; Clinical Genetics; Klinisk genetik; Molekylär medicin; Molecular Medicine; Oncology; Onkologi; Medicin; Medicine; Medical Genetics; Medicinsk genetik;

    Abstract : The clinical course of chronic lymphocytic leukemia (CLL) is highly heterogeneous, which has prompted the search for biomarkers that can predict prognosis in this disease. The IGHV gene mutation status and certain genomic aberrations have been identified as reliable prognostic markers of clinical outcome for this disorder. READ MORE

  4. 9. Phylogeny and species delimitation in Roccellaceae and Physciaceae (Euascomycetes)

    Author : Katileena Lohtander; Mats Wedin; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Systematics and phylogenetics; Systematik och fylogeni; systematisk botanik; Systematic Botany;

    Abstract : DNA sequence data (the ITS region and Group I Introns) from the nuclear ribosomal repeat (rDNA), partial β-tubulin gene sequences, RAPD markers, and some morphological characters were analysed phylogenetically in order to examine relationships in lichenized Euascomycetes, from the species level to higher taxonomic levels. The species level studies comprise some so-called species pairs in two families, Roccellaceae (Arthoniales) and Physciaceae (Lecanorales). READ MORE

  5. 10. Genetic, morphological and chemical variation in the genus Harpagophytum

    Author : Mbaki Muzila; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Harpagophytum procumbens is a valuable medicinal plant but mistakes with plant identification at harvesting, and wilful adulteration using the presumably less efficient H. zeyheri are suggested. A multidisciplinary study with plant material from Botswana was conducted. READ MORE