Search for dissertations about: "Biological Sciences Biophysics"

Showing result 1 - 5 of 325 swedish dissertations containing the words Biological Sciences Biophysics.

  1. 1. Development of novel bioanalytical assays with single-molecule readout for biomarker detection and drug candidate characterization

    Author : Olov Wahlsten; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; QCM-D; biomarker detection; TIRF microscopy.; Bioanalytical assay; spectrofluorometry; fluorescence; single-molecule readout; drug discovery; liposomes;

    Abstract : Bioanalytical assays with single-molecule readout for studying molecular interactions have in the past decades received increasing attention. The high sensitivity often offered by this readout scheme has for example enabled ultra-sensitive analyte detection, having important implications for monitoring early disease progression and the effects of drug treatment. READ MORE

  2. 2. Intramolecular isotope analysis reveals plant ecophysiological signals covering multiple timescales

    Author : Thomas Wieloch; Jürgen Schleucher; Mats Nilsson; Gerd Gleixner; Lisa Wingate; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NMR spectroscopy; tree ring; isotope ratio; isotope effect; intramolecular 13C 12C signal; carbon allocation; acclimation; plant performance; climate reconstruction; plant ecophysiology;

    Abstract : Our societies' wellbeing relies on stable and healthy environments. However, our current lifestyles, growth-oriented economic policies and the population explosion are leading to potentially catastrophic degradation of ecosystems and progressive disruption of food chains. READ MORE

  3. 3. Stochastic modelling and analysis of early mouse development

    Author : Sofia Tapani; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; correlation; CUSUM; mouse; non-stationarity; pronucleus; stochastic differential equation; time series; wavelet decomposition; yeast; CUSUM;

    Abstract : The aim of this thesis is to model and describe dynamical events for biological cells using statistical and mathematical tools. The thesis includes five papers that all relate to stochastic modelling of cells. READ MORE

  4. 4. Functional polymer brush coatings for nanoscale devices

    Author : John Andersson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; poly ethylene glycol ; nanopores; electrochemistry; silatranes; func- tional materials; polymer brush; Nanobiotechnology; interpolymer complex; pH re- sponsive; macromolecular gating.;

    Abstract : Nanobiotechnology is an interdisciplinary field that has garnered considerable attention for offering exciting new opportunities of studying and manipulating biomolecules at the nanoscale. This prospect bears large potential benefits in the field of medicine and the whole life science sector in general. READ MORE

  5. 5. Exploring the Interplay of Lipids and Membrane Proteins

    Author : Candan Ariöz; Åke Wieslander; Daniel O. Daley; Malcolm East; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Membrane lipids; membrane proteins; anionic lipids; membrane remodeling; intracellular vesicles; model membrane systems; glycosyltransferase; Escherichia coli; lipid composition; fatty acid modification; membrane curvature; bacterial homeoviscous adaptation; Biochemistry; biokemi;

    Abstract : The interplay between lipids and membrane proteins is known to affect membrane protein topology and thus have significant effect (control) on their functions. In this PhD thesis, the influence of lipids on the membrane protein function was studied using three different membrane protein models. READ MORE