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Showing result 1 - 5 of 14 swedish dissertations matching the above criteria.
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1. Developmental exposure to mixtures of environmental pollutants : Studies on metabolism, developmental processes, and reproductive organs in zebrafish and chicken embryos
Abstract : Humans and wildlife are continuously exposed to mixtures of environmental pollutants. Mixture toxicity can be challenging to predict due to interactions between chemicals and thus whole-mixture approaches are crucial in toxicology. READ MORE
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2. Impact of epidemiologically identified mixtures of endocrine disrupting chemicals on metabolic programming
Abstract : We are ubiquitously exposed to a plethora of endocrine-disrupting chemicals (EDCs), i.e. substances that alter the function(s) of the endocrine system. While ample evidence show individual EDC's influence on developmental processes resulting in adverse health outcomes, less is known about the effects of human-relevant EDC mixtures exposure. READ MORE
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3. In Vitro Studies of Adrenocorticolytic DDT Metabolites, with Special Focus on 3-methylsulfonyl-DDE
Abstract : The DDT metabolite 3-methylsulfonyl-DDE (3-MeSO2-DDE) is bioactivated by cytochrome P450 11B1 (CYP11B1) in the adrenal cortex of mice and forms irreversibly bound protein adducts, reduces glucocorticoid secretion, and induces cell death selectively in cortisol-producing adrenocortical cells. 3-MeSO2-DDE has therefore been proposed as a lead compound for an improved adrenocortical carcinoma (ACC) therapy. READ MORE
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4. Cellular transport and secretion of the cyanobacterial neurotoxin BMAA into milk and egg : Implications for developmental neurotoxicity
Abstract : The cyanobacterial amino acid β-N-methylamino-L-alanine (BMAA) is a neurotoxin implicated in the etiology of neurodegenerative diseases. Cyanobacteria are cosmopolitan organisms present in various environments. READ MORE
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5. Pheromonal Mediated Behaviour and Endocrine Responses in Salmonids : The impact of Cypermethrin, Copper, and Glyphosate
Abstract : The effects of cypermethrin, copper and glyphosate on the endocrine system and subsequent response to female pheromones were investigated in mature male brown trout (Salmo trutta) parr. Responses measured were the amount of strippable milt, blood plasma levels of both an androgen (11-ketotestosterone (11-KT)) and a progestin (17α,20β-dihydroxy-4-pregnen-3-one (17,20b-P)), and behavioural changes. READ MORE