Search for dissertations about: "Biology with specialization in Molecular Biology"
Showing result 1 - 5 of 134 swedish dissertations containing the words Biology with specialization in Molecular Biology.
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1. Evolutionary and Pharmacological Studies of NPY and QRFP Receptors
Abstract : The neuropeptide Y (NPY) system consists of 3-4 peptides and 4-7 receptors in vertebrates. It has powerful effects on appetite regulation and is involved in many other biological processes including blood pressure regulation, bone formation and anxiety. READ MORE
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2. Adenovirus for Cancer Therapy : With a Focus on its Surface Modification
Abstract : Adenovirus serotype 5 (Ad5) is widely used as an oncolytic agent for cancer therapy. However, its infectivity is highly dependent on the expression level of coxsackievirus-adenovirus receptor (CAR) on the surface of tumor cells. READ MORE
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3. Two Types of Fibrils in ATTR Amyloidosis : Implications for Clinical Phenotype and Treatment Outcome
Abstract : Systemic amyloidoses are a group of lethal diseases where proteins aggregate into fibrillar structures, called amyloid fibrils, that deposits throughout the body. Transthyretin (TTR) causes one type of amyloidosis, in which the aggregates mainly infiltrate nervous and cardiac tissue. READ MORE
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4. Long Noncoding RNA Mediated Regulation of Imprinted Genes
Abstract : Genomic imprinting is an epigenetic phenomenon that causes a subset of mammalian genes to be expressed from only one allele in a parent-of-origin manner. The defects in the imprinting regulation result in disorders that affect development, growth and metabolism. READ MORE
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5. Modelling Approaches to Molecular Systems Biology
Abstract : Implementation and analysis of mathematical models can serve as a powerful tool in understanding how intracellular processes in bacteria affect the bacterial phenotype. In this thesis I have implemented and analysed models of a number of different parts of the bacterium E. coli in order to understand these types of connections. READ MORE
