Search for dissertations about: "Biology with specialization in Molecular Biotechnology"
Showing result 21 - 25 of 30 swedish dissertations containing the words Biology with specialization in Molecular Biotechnology.
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21. How precise is cyclic life? : Insights during a single molecule revolution of the bacterial cell cycle
Abstract : Bacterial cells reproduce by doubling in size and dividing. The molecular control systems which regulate the cell cycle must do so in a manner which maintains a similar cell size over many generations. A cell can under conditions of fast growth conclude cell cycles in shorter time than the time required to replicate its chromosome. READ MORE
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22. Molecular simulations of G protein-coupled receptors : A journey into structure-based ligand design and receptor function
Abstract : The superfamily of G protein-coupled receptors (GPCRs) contains a large number of important drug targets. These cell surface receptors recognize extracellular signaling molecules, which stimulates intracellular pathways that play major roles in human physiology. READ MORE
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23. Reaction-Diffusion kinetics of Protein DNA Interactions
Abstract : Transcription factors need to rapidly find one specific binding site among millions of nonspecific sites on the chromosomal DNA. In this thesis I use various aspects of reaction-diffusion theory to investigate the interaction between proteins and DNA and to explain the searching, finding and binding to specific operator sites. READ MORE
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24. Development and improvement of methods for characterization of HPLC stationary phases
Abstract : High Performance Liquid Chromatography (HPLC) is a widely used tech-nique both for detecting and purifying substances in academy and in the industry. In order to facilitate the use of, and knowledge in HPLC, character-ization of stationary phases is of utmost importance. READ MORE
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25. Harnessing the molecular Trojan horse : Evaluating properties of preclinical Aβ immunoPET radioligands for optimized brain delivery via the transferrin receptor
Abstract : With high specificity and selectivity to targets, antibodies are prime candidates for positron emission tomography (PET) radioligands. They do not passively cross the blood-brain barrier which has hindered their development for imaging intrabrain targets, like amyloid-β (Aβ) in Alzheimer’s disease. READ MORE