Search for dissertations about: "Biology with specialization in Molecular Immunology"

Found 5 swedish dissertations containing the words Biology with specialization in Molecular Immunology.

  1. 1. Hematopoiesis in a Crustacean

    Author : Xionghui Lin; Irene Söderhäll; Kenneth Söderhäll; Michael J. Williams; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; astakine; cytokine; hematopoiesis; prokineticin; transglutaminase; ATP synthase; innate immunity; apoptosis; Immunology; Immunologi; Biology with specialization in Comparative Physiology; Biologi med inriktning mot jämförande fysiologi;

    Abstract : Hemocytes (blood cells) play an important role in the immune response in invertebrates, and thus the regulation of hemocyte homeostasis (hematopoiesis) is essential for the host survival against pathogens. Astakine 1, a homologue to vertebrate prokineticins, was first identified in the freshwater crayfish Pacifastacus leniusculus as a cytokine, and was found to be necessary for new hemocyte synthesis and release in vivo, and also to induce spreading and proliferation of Hematopoietic tissue cells (Hpt cells, precursor of hemocytes) in vitro. READ MORE

  2. 2. Mechanisms in Tendon Healing : Pain, Biomarkers and the Role of Mast Cells

    Author : Abdul Alim; Magnus Peterson; Gunnar Pejler; Per Kristiansson; Paul W. Ackermann; Gustav Andersson; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; Tendon Healing; Pain; Biomarkers; Mast Cells; Inflammation; Microdialysis; Neurotransmitters; Glutamate Receptors; Procollagen; Transcriptional factors; Biologi med inriktning mot molekylär immunologi; Biology with specialization in Molecular Immunology; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Neuroscience; Neurovetenskap;

    Abstract : Tendon injuries and tendinopathy are common disorders, but the underlying mechanisms are not well understood. The overall aim of this thesis was to better understand the mechanisms underlying tendon healing, pain, and inflammation. READ MORE

  3. 3. Function and Regulation of B-cell Subsets in Experimental Autoimmune Arthritis

    Author : Anna-Karin E. Palm; Sandra Kleinau; Susanna Cardell; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; B cells; marginal zone; autoimmune arthritis; spleen; lymph node; antigen presentation; Fc gamma receptor IIb; complement receptors 1 and 2; mast cells; Biologi med inriktning mot molekylär immunologi; Biology with specialization in Molecular Immunology;

    Abstract : B lymphocytes play a significant role in autoimmune arthritis, with their function stretching beyond autoantibody production to cytokine secretion and presentation of autoantigen. However, the involvement and activation of different B-cell subset in the autoimmune response is not fully clear. READ MORE

  4. 4. Cancer Immunotherapy : Evolving Oncolytic viruses and CAR T-cells

    Author : Mohanraj Ramachandran; Magnus Essand; Di Yu; Justyna Leja-Jarblad; Richard Vile; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncolytic virus; Adenovirus; Semliki Forest virus; Cancer immunology; Chimeric antigen receptor T-cells; Immunologi; Immunology; Oncology; Onkologi; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Abstract : In the last decade cancer immunotherapy has taken huge strides forward from bench to bedside and being approved as drugs. Cancer immunotherapy harnesses the power of patient’s own immune system to fight cancer. READ MORE

  5. 5. Transcriptional and morphological analysis of organ donor pancreata

    Author : Anton Stenwall; Oskar Skog; Lena Eliasson; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pancreas; Diabetes; Islet of Langerhans; Beta-cell; Immunology; Inflammation; Ageing; Biology with specialization in Molecular Immunology; Biologi med inriktning mot molekylär immunologi;

    Abstract : The diabetes disease panorama affects more than 400 million people world wide – a number projected to rise above 640 million in the next 20 years. Type 1 and type 2 diabetes are associated with adverse complications, resulting in severe morbidity and high healthcare costs exerting substantial strain on society. READ MORE