Search for dissertations about: "Biology with specialization in Structural Biology"

Showing result 21 - 25 of 46 swedish dissertations containing the words Biology with specialization in Structural Biology.

  2. 21. Calculations of Reaction Mechanisms and Entropic Effects in Enzyme Catalysis

    Author : Masoud Kazemi; Johan Åqvist; Per E. M. Siegbahn; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Enzyme catalysis; Entropy; Cytidine deamination; Ribosome; Peptidyl-tRNA hydrolysis; Peptide bond formation; Empirical valence bond method; Density functional theory; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi; Biokemi; Biochemistry; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Abstract : Ground state destabilization is a hypothesis to explain enzyme catalysis. The most popular interpretation of it is the entropic effect, which states that enzymes accelerate biochemical reactions by bringing the reactants to a favorable position and orientation and the entropy cost of this is compensated by enthalpy of binding. READ MORE

  4. 22. Selection during Early Life Stages and Local Adaptation in Arabidopsis thaliana

    Author : Froukje M. Postma; Jon Ågren; Kathleen Donohue; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Dormancy cycling; Germination timing; Maternal effects; Natural variation; QTL mapping; Seed bank; Seed dormancy; Structural Equation Modeling; Biology with specialization in Ecological Botany; Biologi med inriktning mot ekologisk botanik;

    Abstract : Organisms are often adapted to their local environment, but the role of early life stages in adaptive differentiation among populations remains poorly known. The aim of my thesis was to investigate the contribution of early life stages to the magnitude and genetic basis of local adaptation, and to identify the underlying adaptive traits. READ MORE

  5. 23. Molecular Metamorphosis in Transcriptional Regulation

    Author : Malin Lüking; Johan Elf; Victor Muñoz; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Protein-DNA interactions; Facilitated diffusion; Binding Kinetics; Molecular Simulations; Fluorescence Microscopy; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Abstract : The foundation of all life is the interaction of molecules. Molecular interaction occurs in the tightly packed cytoplasm. In this crowded environment, the molecules need to be able to establish stable interactions with specific interaction partners, and with specific ones only. READ MORE

  6. 24. Speciation genomics in Ficedula flycatchers

    Author : Madeline Chase; Carina Mugal; Chris Jiggins; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; recombination; linked selection; selective sweeps; sex chromosomes; structural variation; birds; genome assembly; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Abstract : Understanding what evolutionary processes have shaped patterns of genomic differentiation between species is a major aim of speciation genomics. However, disentangling the role of different processes that generate similar patterns remains a substantial challenge. READ MORE

  7. 25. Structural studies on the extracellular flavocytochrome cellobiose dehydrogenase from Phanerochaete chrysosporium

    Author : Martin Hällberg; Andrea Mattevi; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; cellobiose dehydrogenase; flavocytochrome; hydride transfer; radical mechanism; X-ray crystallography; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; Biology; with specialization in structural biology; biologi; med inriktning mot strukturbiologi;

    Abstract : Microorganisms that degrade lignocellulose play an important role in maintaining the global carbon cycle. Under cellulolytic conditions, the fungus Phanerochaete chrysosporium produces an extracellular flavocytochrome, cellobiose dehydrogenase (CDH), with a proposed role in lignocellulose degradation. READ MORE