Search for dissertations about: "Biomarker detection"

Showing result 1 - 5 of 106 swedish dissertations containing the words Biomarker detection.

  1. 1. Strategies for Miniaturized Biomarker Detection

    University dissertation from Department of Biomedical Engineering, Lund university

    Author : Belinda Adler; Lunds universitet.; Lund University.; [2014]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; biomarker; miniturization; lab-on-a-chip; proteomics; PSA; microarray; mass spectrometry; MALDI MS; SPE; sample preparation; immunoaffinity; antibody; aptamer; mass tag; ISET.;

    Abstract : Popular Abstract in Swedish Prostatacancer är en av de vanligaste förekommande cancerformerna. Många äldre män har cancerceller i sin prostata, men som tur är behöver inte all cancer behandlas eftersom den inte växer. I USA får ungefär 27% av alla män prostatacancer och cirka 10% dör av det. READ MORE

  2. 2. Molecular Tools for Biomarker Detection

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Lei Chen; Uppsala universitet.; Uppsala universitet.; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Rolling circle amplification; padlock probe;

    Abstract : The advance of biological research promotes the emerging of new methods and solutions to answer the biological questions. This thesis describes several new molecular tools and their applications for the detection of genomic and proteomic information with extremely high sensitivity and specificity or simplify such detection procedures without compromising the performance. READ MORE

  3. 3. Development of novel bioanalytical assays with single-molecule readout for biomarker detection and drug candidate characterization

    University dissertation from ; Chalmers tekniska högskola; Gothenburg

    Author : Olov Wahlsten; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; QCM-D; biomarker detection; TIRF microscopy.; Bioanalytical assay; spectrofluorometry; fluorescence; single-molecule readout; drug discovery; liposomes;

    Abstract : Bioanalytical assays with single-molecule readout for studying molecular interactions have in the past decades received increasing attention. The high sensitivity often offered by this readout scheme has for example enabled ultra-sensitive analyte detection, having important implications for monitoring early disease progression and the effects of drug treatment. READ MORE

  4. 4. Integrative approaches in ecotoxicological testing: Implications for biomarker development and application

    University dissertation from Stockholm : Department of Applied Environmental Science, Stockholm University

    Author : Sara Furuhagen; Stockholms universitet.; [2013]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; biomarker; oxidative stress; Daphnia magna; Applied Environmental Science; tillämpad miljövetenskap;

    Abstract : Ecotoxicology aims to understand toxic effects of chemicals in the environment. Effects can be observed at different levels of the biological organization, from molecular to ecosystem level. READ MORE

  5. 5. Significance of Wilms’ tumor gene 1 as a biomarker in acute leukemia and solid tumors

    University dissertation from Umeå : Umeå University

    Author : Charlotta Andersson; Umeå universitet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Wilms’ tumor gene 1; biomarker; leukemia; renal cell carcinoma; ovarian carcinoma; Clinical Chemistry; klinisk kemi; patologi; Pathology;

    Abstract : Wilms’ tumor gene 1 (WT1) is a zinc finger transcriptional regulator with crucial functions in embryonic development. Originally WT1 was described as a tumor suppressor gene, but later studies have shown oncogenic properties of WT1 in a variety of tumors. Because of its dual functions in tumorigenesis, WT1 has been described as a chameleon gene. READ MORE