Search for dissertations about: "Biomarker detection"
Showing result 16 - 20 of 160 swedish dissertations containing the words Biomarker detection.
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16. Determination of biomarkers for lipid peroxidation and oxidative stress : Development of analytical techniques and methods
Abstract : Oxidative stress can be defined as a state of disturbance in the pro-oxidant/antioxidant balance in favour of the former, leading to potential damage. Processes associated with oxidative stress involve reactive oxygen species and radicals and can result in elevated levels of oxidatively modified or toxic molecules that can cause cellular malfunction, and even cell death. READ MORE
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17. Systemic effects after ionizing radiation exposure: Genome-wide transcriptional analysis of mouse normal tissues exposed to (211)At, (131)I, or 4 MV photon beam
Abstract : The radionuclides 131I and 211At are used or proposed for a variety of cancer treatments. Both radiohalogens exhibit considerable uptake in the thyroid gland and–to a lower degree–in various other tissues if they are unbound or released from a cancer-targeting agent. READ MORE
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18. Quality Control for high-throughput Quantitative Proteomics - Harnessing the potential of label-free LC-MS
Abstract : Multiplex protein quantification, proteomics, is essential for uncovering new biomarkers and understanding biology. Liquid chromatography coupled to mass spectrometry (LC-MS) is the predominant technique for these measurements. READ MORE
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19. Biomarkers of exposure to pesticides in humans
Abstract : Almost every human is exposed to pesticides, in work environments, by domestic use and via diet, drinking water and personal products. Current research expresses concern that low dose exposure over time can lead to adverse health effects. READ MORE
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20. Role of mitochondria in early molecular diagnosis and prognosis of cancer
Abstract : Background:Earlier clinical detection of cancer may improve survival as well as offer opportunities for less invasive treatment options. This thesis explores whether the mitochondria and its related genes in the nuclear genome can be used as novel methods for the diagnosis and prognosis of cancers. READ MORE