Search for dissertations about: "Biomarker discovery"
Showing result 16 - 20 of 93 swedish dissertations containing the words Biomarker discovery.
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16. Biomarkers for Better Understanding of the Pathophysiology and Treatment of Chronic Pain : Investigations of Human Biofluids
Abstract : Chronic pain affects 20 % of the global population, causes suffering, is difficult to treat, and constitutes a large economic burden for society. So far, the characterization of molecular mechanisms of chronic pain-like behaviors in animal models has not translated into effective treatments. READ MORE
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17. Antibody-based bead arrays for high-throughput protein profiling in human plasma and serum
Abstract : Affinity-based proteomics utilizes affinity binders to detect target proteins in a large-scale manner. This thesis describes a high-throughput method, which enables the search for biomarker candidates in human plasma and serum. READ MORE
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18. Proteomic profiling of bacterial host adaptation : Racing the Red Queen
Abstract : Despite the discovery of antibiotics almost a century ago, infectious diseases continue to be a substantial cause of human mortality and morbidity worldwide, especially in developing countries. The adverse affects of infectious diseases are thought to increase over the coming years as the widespread misuse of antibiotic leads to the emergence of strains for which current therapies are ineffective. READ MORE
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19. Bioimaging for analysis of protein expression in cells and tissues using affinity reagents
Abstract : The detection and analysis of biomolecules, such as proteins, are of great interest since these molecules are fundamental for life and our health. Due to the complexity of biological processes, there is a great advantage of studying proteins in their natural context, for example by using bioimaging. READ MORE
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20. The immune microenvironment in mantle cell lymphoma : Targeted liquid and spatial proteomic analyses
Abstract : The complex interplay of the tumour and immune cells affects tumour growth, progression, and response to treatment. Restorationof effective immune response forms the basis of onco-immunology, which further enabled the development of immunotherapy. READ MORE