Search for dissertations about: "Biomarker"

Showing result 21 - 25 of 776 swedish dissertations containing the word Biomarker.

  2. 21. Fluid biomarkers of extracellular matrix remodelling across neurological diseases

    Author : Karolina Minta; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; biomarker; extracellular matrix; idiopathic normal pressure hydrocephalus; immunoassay; mass spectrometry; radiation-induced brain injury; traumatic brain injury; vascular dementia;

    Abstract : Neurological diseases constitute a major health and socioeconomic issue. Despite an enormous amount of research going on globally, the prevalence and mortality of neurological disorders are still rising. READ MORE

  4. 22. Measurement of T1 relaxation time in lungs - Preclinical and clinical MRI applications to COPD

    Author : Daniel Alamidi; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Magnetic Resonance Imaging; biomarker; tobacco smoke; mouse; smoking; lung imaging; Chronic Obstructive Pulmonary Disease; ultrashort echo time UTE ; T1 mapping; longitudinal relaxation time;

    Abstract : Monitoring of regional lung function in clinical trials of chronic obstructive pulmonary disease (COPD) requires alternative endpoints beyond global pulmonary function tests (PFTs), which is the most common approach for diagnosing lung function abnormalities in humans. A promising magnetic resonance imaging (MRI) biomarker of lung disease in humans and animals is the T1 relaxation parameter. READ MORE

  5. 23. Increasing the interpretability of Alzheimer-related biomarkers: cell- and cerebrospinal fluid-based studies with focus on neurogranin

    Author : Faisal Hayat Nazir; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; biomarker; neurogranin; APP; human iPSCs; CSF;

    Abstract : Biomarkers for Alzheimer’s disease (AD) is a growing field of research. A particularly vibrant field during recent years has been biomarkers for synaptic dysfunction. READ MORE

  6. 24. Advances and Applications of Antibody Arrays - Proteomic Profiling of Pancreatic Disease

    Author : Anna Sandström Gerdtsson; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteomics; affinity proteomics; antibody microarray; pancreatic cancer; pancreatitis; biomarker; immunosignature;

    Abstract : Recombinant antibody microarrays have advanced into indispensable tools for large-scale, high-throughput multiplexed serum proteomics. This thesis, based upon five original papers, deals with the development of an in-house designed antibody microarray platform, and its applications for serum profiling of pancreatic disease. READ MORE

  7. 25. Pharmaceuticals – improved removal from municipal wastewater and their occurrence in the Baltic Sea

    Author : Berndt Björlenius; Gen Larsson; Antonius J. A. van Maris; Hallvard Ødegaard; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Advanced wastewater treatment; WWTP; pilot plant; pharmaceutical residues; removal of pharmaceuticals; activated carbon; ozonation; nanofiltration; biomarker; Baltic Sea; Bioteknologi; Biotechnology;

    Abstract : Pharmaceutical residues are found in the environment due to extensive use in human and veterinary medicine. The active pharmaceutical ingredients (APIs) have a potential impact in non-target organisms. Municipal wastewater treatment plants (WWTPs) are not designed to remove APIs. READ MORE