Search for dissertations about: "Biomarkers and medications"
Showing result 1 - 5 of 14 swedish dissertations containing the words Biomarkers and medications.
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1. Cholesterol metabolism in breast cancer: Prognostic factors and optimizing treatment
Abstract : AbstractBreast cancer (BC) is the most common cancer among women in Sweden and worldwide. Adjuvant endocrine therapies are effective, yet 20-30% patients experience disease relapse. Altered cholesterol metabolism is an emerging hallmark of breast cancer proliferation and endocrine therapy resistance. READ MORE
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2. The significance of low-grade inflammation in the gastrointestinal tract
Abstract : BackgroundGastrointestinal (GI) symptoms are commonly reported in a normal population. Mostly, the symptoms are of benign cause but occasionally the symptoms can be signs of a more harmful disease. In general, it is difficult to distinguish whether the reported symptoms are caused by a benign (functional) or organic (i.e. READ MORE
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3. Genetic and phenotypic discordance in cardiometabolic diseases
Abstract : Cardiometabolic conditions such as obesity and type 2 diabetes (T2D) are among the first causes of death globally, and the number of people affected is rapidly increasing. Both conditions are intricately connected and are associated with many life-threatening cardiovascular disease (CVD). READ MORE
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4. Redefining suicidal behaviour – Rating scales and biomarkers
Abstract : Risk assessment of suicidal behaviour is one of the most important tasks in clinical psychiatry and a major determinant of subsequent care and treatment selections. To date, suicide risk assessment is based solely on clinical evaluations, which inevitably leads to subjective interpretations and decisions by the psychiatrist. READ MORE
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5. Prevalence and Prognostic Impact of Periodontal Disease and Conventional Risk Factors in Patients with Stable Coronary Heart Disease
Abstract : The purpose of this thesis was to assess the prevalence and management of established cardiovascular (CV) risk factors and the prevalence and influence of self-reported markers (number of teeth and frequency of gum bleeding) of periodontal disease (PD), a less explored CV risk factor, in patients with stable chronic coronary heart disease (CHD).We studied patients from the global STabilization of Atherosclerotic plaque By Initiation of darapLadIb TherapY (STABILITY) trial (n=15,828), in which patients with stable chronic CHD were randomized to either darapladib or placebo. READ MORE