Search for dissertations about: "Biosensor"

Showing result 1 - 5 of 188 swedish dissertations containing the word Biosensor.

  1. 1. Revealing Secrets of Synaptic Protein Interactions A Biosensor based Strategy

    Author : Christian Seeger; U Helena Danielson; Sarah Lummis; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surface plasmon resonance; biosensor; AMPA receptor; GABAA receptor; ligand-gated ion channel; A-kinase anchoring protein; caldendrin; calmodulin; HIV; fragment based drug discovery; Biokemi; Biochemistry; Neuroscience; Neurovetenskap;

    Abstract : Protein interactions are the basis of synaptic function, and studying these interactions on a molecular level is crucial for understanding basic brain function, as well as mechanisms underlying neurological disorders. In this thesis, kinetic and mechanistic characterization of synaptic protein interactions was performed by using surface plasmon resonance biosensor technology. READ MORE

  2. 2. Differential Magnetic Biosensor using HTS SQUID Gradiometer

    University dissertation from Gothenburg : Chalmers tekniska högskola

    Author : Sobhan Sepehri; [2019]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; high-Tc SQUID; magnetic bioassay; diagnostics; RCA; microfluidics; magnetic nanoparticle; point-of-care; rolling circle amplification; differential ac susceptibility; biosensor;

    Abstract : A fundamental tool for containing an epidemic outbreak and mitigating its effects is early diagnostics. Currently, most of the diagnostic tests are performed by trained staff in centralized labs, which are expensive and time-consuming to establish and operate. Lack of access to such facilities could have devastating effects. READ MORE

  3. 3. Biosensor technology applied to hybridization analysis and mutation detection

    University dissertation from Stockholm : KTH

    Author : Peter Nilsson; [1998]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; biosensor; genosensor; surface plasmon resonance; hybridization; nucleic acids; oligonucleotide; mutation detection; mismatch discrimination; modular; TECHNOLOGY Bioengineering; TEKNIKVETENSKAP Bioteknik;

    Abstract : This thesis demonstrates the application of biosensor technology for molecular biology investigations, utilizing a surface plasmon resonance based optical device for mass sensitive detection of biomolecular interactions at a chipsurface. Oligonucleotide model systems were designed for analysis of the action of DNA manipulating enzymes. READ MORE

  4. 4. Biosensor surface chemistry for oriented protein immobilization and biochip patterning

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Emma Ericsson; Karin Enander; Sofia Svedhem; [2013]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biochip; biosensor; hydrogel; ligand; orientation; patterning; photochemistry; protein immobilization; surface chemistry; self-assembled monolayer; SAM;

    Abstract : This licentiate thesis is focused on two methods for protein immobilization to biosensor surfaces for future applications in protein microarray formats. The common denominator is a surface chemistry based on a gold substrate with a self-assembled monolayer (SAM) of functionalized alkanethiolates. READ MORE

  5. 5. Affinity biosensors based on a capacitive transducer

    University dissertation from Christine Berggren, Iliongränd 11, 224 72 Lund, Sweden

    Author : Christine Berggren; [1998]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; self-assembled monolayers; capacitance; heavy metal ion; non-labeled; nucleic acid; DNA biosensor; Biosensor; immunosensor; Analytical chemistry; Analytisk kemi;

    Abstract : Capacitive biosensors were developed for several analytes such as hormones, interleukines, viruses and heavy metal ions. The sensing surfaces were prepared by immobilizing the biorecognition element to self-assembled monolayers (SAMs) on gold. SAMs form spontaneously on gold by adsorption of thiols, sulfides or disulfides. READ MORE