Search for dissertations about: "Biosynthesis"

Showing result 6 - 10 of 533 swedish dissertations containing the word Biosynthesis.

  2. 6. Functions of Heparan Sulfate During Mouse Development : Studies of Mice with Genetically Altered Heparan Sulfate Biosynthesis

    Author : Maria Ringvall; Lena Kjellén; Erik Forsberg; Ulf Lindahl; Erika Gustafsson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; embryonic development; gene targeting; lung development; ossification; heparan sulfate; heparin; N-deacetylase N-sulfaotransferase; NDST; proteoglycan; morphogen; biosynthesis; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi;

    Abstract : Heparan sulfate (HS) is a ubiquitous polysaccharide on the cell surface and in the extracellular matrix. HS is an important actor in the regulation of cell signaling, especially in the developing embryo. READ MORE

  4. 7. Understanding Heparan Sulfate Biosynthesis and Functional Implications of Heparanase

    Author : Tianyi Song; Dorothe Spillmann; Cathrine Merry; Uppsala universitet; []
    Keywords : Heparan sulfate; biosynthesis; heparanase; lipid metabolism; cancer; cell adhesion; apoptosis.; Molekylär medicin;

    Abstract : Heparan sulfate (HS) proteoglycans are present on the plasma membrane of all animal cells studied so far and are a major component of extracellular matrices. Heparanase is an endo-ß-glucuronidase that cleaves HS chains at internally located ß-glucuronidic linkages1. READ MORE

  5. 8. Enzymes involved in biosynthesis and degradation of heparin-related polysaccharides

    Author : Dagmar Sandbäck Pikas; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; heparin; heparan sulphate; biosynthesis; N-deacetylase N-sulphotransferase; endoglycosidase; heparanase; Biokemi; Biochemistry; Biokemi; Medical and Physiological Chemistry; medicinsk och fysiologisk kemi;

    Abstract : Heparin and heparan sulphate (HS) are structurally related polysaccharides of the glycosaminoglycan type. As the glycan moiety of proteoglycans, they exist covalently linked to various core proteins. READ MORE

  6. 9. Structural and biochemical insights into biosynthesis and degradation of N-glycans

    Author : Tom Reichenbach; Christina Divne; David Drew; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; N-glycan; biosynthesis; degradation; glycosyltransferase; glycoside hydrolase; biofuel; enzyme; membrane protein; Bioteknologi; Biotechnology;

    Abstract : Carbohydrates are a primary energy source for all living organisms, but importantly, they also participate in a number of life-sustaining biological processes, e.g. cell signaling and cell-wall synthesis. The first part of the thesis examines glycosyltransferases that play a crucial role in the biosynthesis of N-glycans. READ MORE

  7. 10. ELOVL2 and PUFA biosynthesis : Impact on sex-specific processes in mammals

    Author : Amanda González-Bengtsson; Anders Jacobsson; Christian Drevon; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; fysiologi; Physiology;

    Abstract : Endogenously synthesized PUFAs (Polyunsaturated Fatty Acids) vary in production depending on medical conditions, gender, developmental phase, age, fertility status, pregnancy and lactation. PUFA biosynthesis is further regulated via amount of dietary intake as well as genetically. READ MORE