Search for dissertations about: "Bioteknologi"
Showing result 1 - 5 of 972 swedish dissertations containing the word Bioteknologi.
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1. Magnetic bead-based isolation of biological therapeutic modalities
Abstract : Biopharmaceutical modalities, such as monoclonal antibodies or the less established cell therapies, are nowadays very important for the treatment of severe or incurable diseases. The manufacturing of such modalities is complex and costly, including the downstream processing, which is highly essential to ensure the safety and quality of the product. READ MORE
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2. Affibody-mediated targeting of HER-family receptors for cancer imaging and therapy
Abstract : Proteins are remarkable molecules with diverse and specialized functions playing essential roles in most biological processes. One such function is protecting us from diseases by the action of antibodies in our immune system that can recognize and mediate the destruction of invading pathogens by binding to foreign epitopes found on non-self proteins. READ MORE
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3. Bifunctional ADAPTs: Opportunity for serological Half-life extension and Targeted therapy
Abstract : Small engineered scaffold proteins (ESPs) gain more and more popularity as biological drugs, due to their specificity and applicability in diagnostics and therapy. Thanks to their high stability, low immunogenicity and low production cost, they present themselves as a promising alternative to the market-leading antibodies. READ MORE
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4. Decellularized liver extracellular matrix as a 3D scaffold for bioengineering applications
Abstract : The increasing global burden of end-stage liver disease has increased the need for liver transplantation, the definitive cure. However, there is a huge discrepancy between the number of available organ donors and the number of patients waiting for transplantation, resulting in the deaths of a significant number of patients on the waiting list as only 10% of the global need for transplantation is met. READ MORE
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5. Recreating the microenvironment of the neurovascular unit
Abstract : The neurovascular unit (NVU) comprises the blood-brain-barrier (BBB) and its surrounding astrocytes, pericytes and neurons that are embedded in the extracellular matrix (ECM). As the main function of the BBB is to protect the brain from inlet of pathogens and toxins, the specialized endothelial cells that keep the barrier tight will also hinder the passage of pharmaceuticals. READ MORE
