Search for dissertations about: "Bladder cancer"

Showing result 1 - 5 of 109 swedish dissertations containing the words Bladder cancer.

  1. 1. Cancer Immunotherapy A Preclinical Study of Urinary Bladder Cancer

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Christina Ninalga; Uppsala universitet.; [2006]
    Keywords : Medicine; immunotherapy; bladder carcinoma; cancer; CpG ODNs; Adenoviral vector; CD40L; TRANCE; Lymphotactin; IL2; IL15; Medicin;

    Abstract : Bacillus Calmette Guérin (BCG), or attenuated Mycobacterium bovis, is the gold standard of immunotherapy in the clinic to treat superficial bladder cancer. However, setbacks remain due to a high recurrence rate, side effects, and BCG-refractory disease. READ MORE

  2. 2. Molecular Classification of Bladder Cancer

    University dissertation from Oncology, Lund

    Author : Gottfrid Sjödahl; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bladder cancer; Subtype; Classification;

    Abstract : Decisions in the treatment of bladder cancer today are based on clinical and pathological risk variables such as tumor stage and tumor grade. The importance of these conventional risk variables is well documented since more than 10 years, and they are used routinely in the clinics. READ MORE

  3. 3. Molecular Characterization of Bladder Cancer Subtypes

    University dissertation from Lund University: Faculty of Medicine

    Author : Pontus Eriksson; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bladder Cancer; Urothelial Carcinoma; Molecular Subtypes; Genomic Characterization; Gene Expression;

    Abstract : Bladder cancer is one of the most common malignancies world-wide, and in Sweden approximately 3000 cases are diagnosed annually. Even though bladder cancer is so common there is low public awareness of the disease, and it has historically been less studied compared to other common types of cancer. READ MORE

  4. 4. Mismatch Repair Deficient Cancer Diagnostic Aspects in Colorectal Cancer and the Role of Urological Cancer in Lynch Syndrome

    University dissertation from Department of Oncology, Clinical Sciences, Lund University

    Author : Patrick Joost; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mismatch repair; Lynch syndrome; immunohistochemistry; microsatellite instability; heterogeneity; cumulative incidence; colorectal cancer; urothelial cancer; prostate cancer; renal cell cancer;

    Abstract : Mismatch repair (MMR) deficiency is carcinogenic and can either have somatic/sporadic causes (i.e. epigenetic silencing or somatic inactivation) or hereditary causes (Lynch syndrome due to a germline mutation in one of the MMR genes ¬- MLH1, MSH2, MSH6, PMS2). READ MORE

  5. 5. Small non-coding RNAs in cancer

    University dissertation from Department of Oncology, Clinical Sciences, Lund University

    Author : Helena Persson; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microRNA; non-coding RNA; breast cancer; CYP3A4; bladder cancer;

    Abstract : The complex genetics of cancer, which allows tumours to grow and spread while bypassing the control circuitry of the cell, involves dysregulation of the genome, transcriptome and proteome. The importance of protein-coding genes such as growth factors and hormone receptors is well established. READ MORE