Search for dissertations about: "Blood group polymorphism"
Showing result 1 - 5 of 31 swedish dissertations containing the words Blood group polymorphism.
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1. Molecular Genetic Studies of the Blood Group ABO Locus in Man
Abstract : The ABO blood group system is undoubtedly the most important genetic and phenotypic marker in clinical transfusion medicine. The A and B determinants are immunodominant, terminally located carbohydrate residues of glycoconjugates on erythrocytes and other cell surfaces. READ MORE
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2. Studies of Thai blood group and platelet polymorphism. Implications for malaria susceptibility
Abstract : The objectives of the thesis were to seek a better understanding of polymorphic RBC surface molecules in the Thai, and to investigate the role of certain blood groups in malarial invasion. MALDI-TOF MS was employed in Study I as an efficient method for genotyping to establish the common blood group and platelet antigen genotypes of 396 blood donors. READ MORE
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3. Elucidating Genetic and Biochemical Aspects of the P1 and Sda Carbohydrate Histo-Blood Group Antigens
Abstract : Human histo-blood groups are inherited polymorphic variants that occur in the molecular structures on the humanred blood cell (RBC) surface. Introducing foreign RBCs into a recipient lacking an antigen may activate the humoraldefence leading to a hemolytic transfusion reaction. READ MORE
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4. Studies on the Polymorphism and Transcriptional Regulation of the ABO and P1PK Histo-blood Group Genes
Abstract : Antigens of the clinically important ABO and P1PK blood group systems are carbohydrate structures. Thus the underlying genes do not encode antigens directly but glycosyltransferases that add specific sugar molecules to selected precursor chains. READ MORE
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5. Molecular genetics of human carbohydrate defined blood groups. Studies of the ABO and P blood group systems
Abstract : The aim of this study was to explore the molecular genetics of the carbohydrate defined blood group ABO and P systems.The blood group ABO system is the clinically most significant system in transfusion medicine. Using modern molecular biology, a number of the ABO alleles have been characterized. READ MORE