Search for dissertations about: "Blood salvage"
Showing result 1 - 5 of 12 swedish dissertations containing the words Blood salvage.
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1. Heparin coating and cardiotomy suction in cardiopulmonary bypass
Abstract : The present thesis addresses various means of reducing inflammatory responses associated with cardiopulmonary bypass (CPB) and retransfusion of pericardial suction blood (PSB) during cardiac surgery. Four (I-IV) prospective randomised controlled clinical trials comprising 475 patients were performed in the following areas: effects of heparin coating on measures of clinical outcome and memory function (I, II), inflammatory reactions in PSB and its systemic effects after retransfusion using cardiotomy suction or cell salvage (III) and effects of retransfusion of PSB on memory function and release patterns of protein S100B (IV). READ MORE
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2. Salvage and de novo synthesis of nucleotides in Trypanosoma brucei and mammalian cells
Abstract : All living cells are dependent on nucleic acids for their survival. The genetic information stored in DNA is translated into functional proteins via a messenger molecule, the ribonucleic acid (RNA). Since DNA and RNA can be considered as polymers of nucleotides (NTPs), balanced pools of NTPs are crucial to nucleic acid synthesis and repair. READ MORE
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3. Modulation of Inflammatory Response in Surgical Trauma
Abstract : Surgical trauma results in the activation of inflammatory cascade systems in the body. Excessive systemic inflammation can lead to organ dysfunction in one or several organs. READ MORE
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4. Surgical trauma, inflammation and tissue injury
Abstract : Surgical tissue trauma is a strong stimulus for local inflammation, including leukocyte recruitment. While such a response may be of importance for the defense against microorganisms, it is also clear that inflammation may contribute to further tissue injury. READ MORE
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5. Inflammatory responses in minor and major surgical procedures
Abstract : Surgical procedures promote an inflammatory response, correlating to the extent of the procedure performed and influencing outcome after surgery. The aims of the thesis were to investigate factors modulating the inflammatory response perioperatively and to evaluate cell salvage for indications so far not accepted in clinical practice. READ MORE