Advanced search

Showing result 1 - 5 of 96 swedish dissertations matching the above criteria.

  1. 1. Preoperative deposit of autologous blood. Effects on inflammatory mediators

    Author : Monica Hyllner; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allogeneic; autologous; complement; cytokines; blood storage; erythropoiesis; hysterectomy; plasma; prestorage leucocyte filtration; rHuEPO; whole blood.;

    Abstract : Blood contains complex cascade systems and substances that can be activated during the processing of blood components and storage. Allogeneic blood, i.e. blood from someone else, is normally separated into components before storage and transfusion, while autologous blood (the patient s own blood) often is used as whole blood. READ MORE

  2. 2. Towards a detailed understanding of the red blood cell storage lesion : and its consequences for in vivo survival following transfusion

    Author : Andreas Hult; Christer Malm; Per-Arne Oldenborg; Martin L. Olsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Red blood cell; erythrocyte; transfusion; macrophage; phagocytosis; storage lesion; eryptosis; Class A scavenger receptor; transfusion medicine; transfusionsmedicin;

    Abstract : Red blood cells (RBCs) are vital for oxygen delivery to tissues and constitute the vast majority of all cells in blood. After leaving the red bone marrow as mature cells, RBCs have a lifespan of approximately 120 days before they are removed from the circulation by macrophages, mainly in the spleen and liver. READ MORE

  3. 3. Phosphatidylethanol - formation and degradation in blood and organs

    Author : Steina Aradottir; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diagnostik; Public health; Diagnostics; organs; blood; HPLC; in vitro; in vivo; human; rat; phosphatidylethanol; phospholipase D; alcohol; ethanol; epidemiology; Folkhälsa; epidemiologi;

    Abstract : Phosphatidylethanol (PEth) is an abnormal phospholipid formed exclusively by the action of phospholipase D (PLD) in the presence of ethanol. The degradation of PEth is slow and due to its accumulation in some cells the possibility to use PEth as marker of ethanol intake has been proposed. READ MORE

  4. 4. Development of new blood banking strategies for processing and storage of red blood cell components

    Author : Linda Larsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The field of red blood cell (RBC) components has been quite uneventful during the last few decades, save for the experimental exploration of alternative additive solution compositions. The reason is likely that the RBC quality has been good enough and the shelf-life of conventional RBC concentrates (RCC) has been long enough to not really motivate the workload that any dramatic changes would implicate. READ MORE

  5. 5. Multiplexed absolute quantification of blood plasma proteins using targeted proteomics

    Author : David Kotol; Mathias Uhlén; Edfors Fredrik; Roman Zubarev; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; mass spectrometry; targeted proteomics; stable isotope standards; recombinant protein standards; absolute quantification; blood plasma; multiplex analysis; plasma profiling; Biotechnology; Bioteknologi;

    Abstract : Proteins are the molecular building blocks of all living organisms. They are the functioning actors in metabolism and communication, and they give specific architecture and purpose to all tissues. Their abundance is dynamic and can be interpreted and associated to different physiological states or diseases. READ MORE