Search for dissertations about: "Blood transfusion"

Showing result 1 - 5 of 106 swedish dissertations containing the words Blood transfusion.

  1. 1. Towards a detailed understanding of the red blood cell storage lesion : and its consequences for in vivo survival following transfusion

    Author : Andreas Hult; Christer Malm; Per-Arne Oldenborg; Martin L. Olsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Red blood cell; erythrocyte; transfusion; macrophage; phagocytosis; storage lesion; eryptosis; Class A scavenger receptor; transfusion medicine; transfusionsmedicin;

    Abstract : Red blood cells (RBCs) are vital for oxygen delivery to tissues and constitute the vast majority of all cells in blood. After leaving the red bone marrow as mature cells, RBCs have a lifespan of approximately 120 days before they are removed from the circulation by macrophages, mainly in the spleen and liver. READ MORE

  2. 2. Aspects of retransfusion of shed blood in cardiac surgery

    Author : Björn Brondén; Anestesiologi och intensivvård; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CABG; cardiotomy suction; lipid microemboli; porcine study; clinical study; cystatin C; creatinine; iohexol clearance; outcome; retransfusion; transfusion; blood.;

    Abstract : The use of cardiotomy suction during open heart surgery with cardiopulmonary bypass (CPB) has a long tradition and often regarded as mandatory. Recently, studies have described potentially negative effects of cardiotomy suction with activation of the complement system, enhanced inflammatory response, hemolysis and coagulopathy. READ MORE

  3. 3. Fat contamination of pericardial suction blood in cardiac surgery : clinical and experimental studies in perspectives of transfusion logistics

    Author : Micael Appelblad; Gunnar Engström; Krister Lindmark; Anders Jeppsson; Umeå universitet; []
    Keywords : Surgery; blood transfusion; cardiopulmonary bypass; pericardial suction blood; fat contamination; lipid microemboli; density separation; surface adsorption; Kirurgi; Surgery; kirurgi;

    Abstract : Introduction: During cardiac surgery aided by cardiopulmonary bypass (CPB) the autotransfusion of pericardial suction blood (PSB) is regarded mandatory to limit allogeneic blood exposure. PSB is however proposed as a source of lipid microemboli and to contribute to brain damage. READ MORE

  4. 4. Molecular Genetic Studies of the Blood Group ABO Locus in Man

    Author : Martin L Olsson; Avdelningen för hematologi och transfusionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chi sequence; recombination; population studies; blood group serology; erythrocyte; blood transfusion; sequencing; DNA; PCR; genomic; Blood group ABO; allele; Immunology; serology; transplantation; Immunologi; serologi; Clinical genetics; Klinisk genetik;

    Abstract : The ABO blood group system is undoubtedly the most important genetic and phenotypic marker in clinical transfusion medicine. The A and B determinants are immunodominant, terminally located carbohydrate residues of glycoconjugates on erythrocytes and other cell surfaces. READ MORE

  5. 5. The dynamics of red blood cells and iron status during infancy

    Author : Marie Larsson; Lund Pediatrik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Barnreferensintervall; Röda blodkroppar; Erytrocyter; Extremt för tidig födsel; Erytropoes; Klinisk kemi; Järnstatus; Ferritin; sTfR; Neonatologi; Pediatrik; Fetal tillväxthämning; Referensintervall; Pediatric reference intervals; Reference limits; Extremely preterm birth; Fetal growth restriction; Clinical chemistry; Iron status; Red blood cells; Erythrocyte; Transfusion; Ferritin; sTfR; Hemoglobin; Neonatal; Reference intervals; Umbilical cord blood; Infancy; Iron deficiency; Anemia; Acute phase response; soluble Transferrin receptor; Neonatal intensive care; Erythropoiesis; Birth; Infant;

    Abstract : Red blood cell (RBC) and iron status biomarkers are commonly used in clinical diagnostics. However, interpretations of infant test results are inherently challenging. READ MORE