Search for dissertations about: "Bmax values"

Found 3 swedish dissertations containing the words Bmax values.

  1. 1. Galanin : A modulator of serotonin neurotransmission : relevance for depression

    University dissertation from Stockholm : Karolinska Institutet, Department of Neuroscience

    Author : Haleh Razani; Karolinska Institutet.; Karolinska Institutet.; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; galanin; 5-HT1A receptors; 5-HT; 8-OH-DPAT; fluoxetine; robalzotan; passive avoidance; microdialysis; mRNA; KD values; Bmax values; depression;

    Abstract : Abstract-Galanin is widely distributed throughout the central nervous system with multiple and diverse biological roles. In the rat, galanin-like immunoreactivity is expressed in a population of5-hydroxytryptamine (5-HT, serotonin) neurons in the dorsal raphe (DR) with extensive projections to the forebrain areas e.g., hippocampus. READ MORE

  2. 2. In vivo quantification of extrastriatal dopamine D2 receptors in the human brain

    University dissertation from Stockholm : Karolinska Institutet, Department of Clinical Neuroscience

    Author : Hans Olsson; Karolinska Institutet.; Karolinska Institutet.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; FLB 457; positron emission tomography; pituitary; receptor density; affinity; benzamide; Scatchard; saturation; receptor occupancy;

    Abstract : The dopamine D2 receptor subtype attracts considerable attention in research on the patophysiology and drug treatment of several neuropsychiatric disorders, such as schizophrenia and Parkinson s disease. The brain imaging technology Positron Emission Tomography (PET) has since long allowed for reliable quantification of the high density of dopamine D2 receptors in large brain structures such as the neostriatum. READ MORE

  3. 3. Dopamine receptors in the rat brain

    University dissertation from Stockholm : Karolinska Institutet, false

    Author : Mi Hillefors-Berglund; Karolinska Institutet.; Karolinska Institutet.; [1997]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dopamine D2 receptors; Dopamine D3 receptors; Rat; Autoradiography; [3H]7-OH-DPAT; [3H]PD 128907; Caudate-putamen; Subcortical limbic area; Islands of Calleja; CGS 21680; Toluene; Neurotensin; Asphyxia; Aging; Magnesium; GTP;

    Abstract : Dopamine receptors belong to a large superfamily of G protein-coupled receptors and consist of the D1 D2, D3, D4, and D5 receptors. The D2, D3, and D4 receptors belong to the D2 receptor family which is characterized by having a large third cytoplasmic loop and a short C-terminus projecting into the cytosol, and by inhibiting the enzyme adenylyl cyclase. READ MORE