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Showing result 1 - 5 of 23 swedish dissertations matching the above criteria.

2. 1. Coagulase-negative staphylococci in hematological malignancy

   Author : Erik Ahlstrand; Bo Söderquist; Ulf Tidefelt; Karlis Pauksens; Örebro universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coagulase-negative staphylococci; hematological malignancy; Staphylococcus epidermidis; healthcare-associated infection; antibiotic susceptibility; molecular epidemiology; bloddstream infection; bacteremia; Medicine; Medicin;

   Abstract : Bacterial infections are common in hematological malignancy. Coagulase-negative staphylococci (CoNS) are among the most prevalent causes of bacteremia in patients with hematological malignancies. READ MORE

4. 2. Inflammasome polymorphisms and the Inflammatory Response to Bacterial Infections

   Author : Berhane Asfaw Idosa; Eva Särndahl; Anne Kelly; Bo Söderquist; Alexander Persson; Johan Bylund; Örebro universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bacteremia; Cytokines; Gene variants; Inflammasome; Inflammation; Innate immunity; Neutrophils; Meningitis; Neisseria meningitidis; Biomedicin; Biomedicine;

   Abstract : NLRP3 inflammasome; a key component of the innate immune system, can be activated by a number of pathogens and other threats of the body. Activation of the NLRP3 inflammasome triggers caspase-1 mediated maturationof IL-1β and IL-18. READ MORE

5. 3. Molecular epidemiology of methicillin-resistant staphylococcus aureus : epidemiological aspects of MRSA and the dissemination in the community and in hospitals

   Author : Carolina Berglund; Bo Söderquist; Teruyo Ito; Ulf Tidefelt; Johanna Ericson Sollid; Örebro universitet; []
   Keywords : methicillin-resistant Staphylococcus aureus MRSA ; community-acquired MRSA CA-MRSA ; staphylococcal cassette chromosome mec SCCmec ; multilocus sequence typing MLST ; horizontal transfer; Panton Valentine leukocidin PVL ; MEDICINE; MEDICIN; Medicin; Medicine;

   Abstract : Methicillin-resistenta Staphylococcus aureus (MRSA) som bär på genen mecA, har förekommit och spridit sig över hela världen, främst i sjukhusmiljö, och orsakat utbrott av vårdrelaterade (så kallade nosokomiala) infektioner. Dessa infektioner kan inte behandlas med stafylokock-penicilliner och MRSA-bakterierna är ofta resistenta även mot flera andra grupper av antibiotika vilket medför att infektionerna ofta är påtagligt svårbehandlade. READ MORE

6. 4. Dynamics of Human Leukocyte Antigen-D Related expression in bacteremic sepsis

   Author : Sara Cajander; Jan Källman; Kristoffer Strålin; Bo Söderquist; Per Åkesson; Örebro universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; monocyte HLA-DR; sepsis; immunosuppression; bloodstream infection; HLA-DRA; CIITA; qRT-PCR;

   Abstract : Monocytic human leukocyte antigen-D related (mHLA-DR) expression determined by flow cytometry has been suggested as a biomarker of sepsisinduced immunosuppression.In order to facilitate use of HLA-DR in clinical practice, a quantitative real-time PCR technique measuring HLA-DR at the transcription level was developed and evalutated. READ MORE

7. 5. Infection induced chronic inflammation and it's association with prostate cancer initiation and progression

   Author : Sabina Davidsson; Ove Andrén; Bo Söderquist; Jennifer Rider; Gisela Helenius; Jan-Erik Damber; Örebro universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; chronic inflammation; CD4 helper T cells; CD8 cytotoxic T cells; regulatory T cells; Propionibacterium acnes; Medicine; Medicin;

   Abstract : An association between cancer development and inflammation has long been suggested. Approximately 20% of all human cancers in adults are assumed to result from chronic inflammation. The aim of this thesis was to investigate if infection-induced chronic inflammation plays a role in prostate carcinogenesis. READ MORE