Search for dissertations about: "Bone Development: physiology"

Showing result 1 - 5 of 7 swedish dissertations containing the words Bone Development: physiology.

  1. 1. Risk factors for falls and fractures in elderly women. The Malmö OPRA study

    Author : Paul Gerdhem; Ortopedi - klinisk och molekylär osteoporosforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fysiologi; Physiology; muskelsystem; Skelett; muscle system; Skeleton; Falls.; Vitamin D; Bone turnover markers; Frail elderly; Body weight; Physical activity; Osteoporosis; Fractures; Bone density; reumatologi; rheumatology locomotion;

    Abstract : Approximately half of all women will sustain a fracture after the age of 50. Fractures may cause long-term disability and excess mortality. Identifying individuals at high risk of sustaining a fracture is important in the development of primary and secondary prevention strategies. READ MORE

  2. 2. Thyroid hormone receptors and the regulation of bone physiology

    Author : Jenny Kindblom; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : ;

    Abstract : The aim of the studies in this thesis was to investigate the role of thyroid hormone receptors in bone physiology. Thyroid hormone signals through its receptors, the TRs, and has profound effects on bone development and metabolism, as demonstrated in hypo- and hyperthyroidism. READ MORE

  3. 3. The role of autophagy in cartilage physiology and metabolism : implications for growth and ageing

    Author : Karuna Kumari Vuppalapati; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : Cartilage is the main constituent of the embryonic skeleton. At the ends of long bones cartilage forms a growth plate consisting of chondrocytes in distinct stages of differentiation and arranged into three zones. These chondrocytes mediate linear bone growth through synchronized proliferation, differentiation, and production of matrix. READ MORE

  4. 4. Parathyroid hormone-related protein (PTHrP), calcium and human osteoblast-like cells

    Author : Jon A. Tsai; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; hOB cells; PTHrP; cAMP; IGFs; IGFBPs; IL-1ß; TGF-ß; [Ca 2 ]i; [Ca2 ]O;

    Abstract : Parathyroid hormone-related protein (PTHrP) may cause humoral hypercalcernia of malignancy (HHM) when overproduced by malignant tumors, but is also produced in lower amounts under normophysiological conditions in practically all cell types, including osteoblasts. One of the aims of the present study was to investigate interactions between PTHrP and osteoblasts, to elucidate bone-regulating functions of PTHrP. READ MORE

  5. 5. Mesenchymal stromal cells in lung tissue

    Author : Sara Rolandsson Enes; Lungbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mesenchymal stromal cells; lung transplantation; bronchiolitis obliterans syndrome; obliterative bronchiolitis; extracellular matrix;

    Abstract : Mesenchymal stromal cells (MSC) are multipotent cells with immunomodulatory and regenerative properties. During recent years, the interest in using MSC for clinical approaches for various diseases have increased. READ MORE