Search for dissertations about: "Bone Morphogenetic Protein 4"

Showing result 1 - 5 of 16 swedish dissertations containing the words Bone Morphogenetic Protein 4.

  1. 1. Survival of onlay bone grafts. A study in the adult rat

    Author : Monica Gordh; Lunds universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rats; polytetrafluoroethylene; artificial; membrane; immunohistochemistry; cortical perforations; bone morphogenetic protein; bone marrow; bone; bone grafts; Odontologi; stomatology; Odontology; skull; tibia;

    Abstract : The aim of this thesis was to study onlay bone grafting in the adult rat to improve graft incorporation and perservation of graft size. In 167 adult isogeneic lewis rats, the size maintenance and bone formation at the graft-host interface of uni- and bicortical onlays positioned in various environments and treatments were investigated. READ MORE

  2. 2. Biomaterials for Promoting Self-Healing of Bone Tissue

    Author : Sonya Piskounova; Jöns Hilborn; Tim Bowden; Simon Cool; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; MEDICAL AND HEALTH SCIENCES; Osseointegration; implant coating; hyaluronan hydrogel; bone morphogenetic protein-2; hydroxyapatite; bone; delivery system; injectable; mixing; radioactive labeling; Kemi med inriktning mot polymerkemi; Chemistry with specialization in Polymer Chemistry;

    Abstract : The present work addresses poor bone/implant integration and severe bone defects. In both conditions external stimuli is required for new bone to form. READ MORE

  3. 3. Molecular regulators in cartilage and bone formation

    Author : Thomas Engstrand; Uppsala universitet; []
    Keywords : Medical sciences; cartilage; bone; TGF-beta; BMP; noggin; gene therapy; gene targeting; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : Cartilage functions as a scaffold for bone formation during development. This process, endochondral ossification, is regulated by systemic hormones and local growth factors. READ MORE

  4. 4. Allograft bone in hip revision: the effect of locally applied pharmacological treatment

    Author : Ola Belfrage; Lund Ortopedi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allograft bone; bone transplantation; bisphosphonate; bone morphogenetic proteins; hip revision; radiostereometric analysis;

    Abstract : The clinical success of primary hip replacement is paramount but the need for revisions will continue to increase due to the increasing number of operated individuals. In Sweden, the number of hip revisions in 2012 exceeded 2,300. During implant loosening, some of the bone in the femur is lost, which can make the revision more difficult. READ MORE

  5. 5. Hyaluronan Derivatives and Injectable Gels for Tissue Engineering

    Author : Kristoffer Bergman; Tim Bowden; Jöns Hilborn; Jeffrey Hubbell; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Hyaluronan; Hydrogel; Tissue Engineering; Scaffold; Minimally invasive strategy; Bone morphogenetic protein; Hydroxyapatite; Bone; Cartilage; Tendon; Polymer chemistry; Polymerkemi;

    Abstract : The present work describes the preparation of hyaluronan derivatives and hydrogels with potential use in tissue engineering applications. A potentially injectable hydrogel consisting of hyaluronan and collagen was successfully used to grow neurons in vitro by encapsulation of neural stem and progenitor cells. READ MORE