Search for dissertations about: "Bone markers"

Showing result 11 - 15 of 194 swedish dissertations containing the words Bone markers.

  1. 11. Influence of bone-associated and cardiovascular biomarkers on vascular events and mortality in relation to renal dysfunction

    Author : Ping-Hsun Wu; Östen Ljunggren; Bengt Fellström; Torbjörn Linde; Jonas Spaak; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; biomarkers; bone markers; cardiovascular markers; proteomics; vascular event; mortality; renal function; hemodialysis; Medicinsk vetenskap; Medical Science;

    Abstract : Biomarkers can help physicians identify subjects with an increased cardiovascular risk. Apart from the clinical factors, some biomarkers have been recognized as important predictors and risk factors for cardiovascular disease in renal disease. READ MORE

  2. 12. Vitamin D, bone turnover markers and hCAP-18 in children with hemato-oncological diseases

    Author : Natalja Jackmann; Per Frisk; Outi Mäkitie; Jan Gustafsson; Anna Sällfors Holmqvist; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vitamin D; pediatric cancer; leukemia; bone marrow failure; hCAP-18; bone turnover markers; Medicinsk vetenskap; Medical Science;

    Abstract : Children with hemato-oncological diseases may have significant skeletal morbidities. Vitamin D is essential for the maintenance of skeletal health and may also be important for immunological functions and cancer outcomes. READ MORE

  3. 13. Novel Insights into Inflammatory Disturbed Bone Remodelling

    Author : Elin Kindstedt; Pernilla Lundberg; Östen Ljunggren; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bone; osteoblast; osteoclast; chemokines; CCL11; periodontitis; rheumatoid arthritis; innate lympoid cells; odontologi; Odontology; immunologi; Immunology; biology; biologi; reumatologi; rheumatology;

    Abstract : Bone is a dynamic tissue that is continuously remodelled, a process that requires equal amounts of osteoclastic bone resorption and osteoblastic bone formation. Inflammation may disturb the equilibrium and result in local and/or systemic bone loss. Negative bone mass balance occurs in several chronic inflammatory diseases, e.g. READ MORE

  4. 14. The osteogenic potential of human mesenchymal stem cells: Novel markers and key factors for differentiation

    Author : Cecilia Granéli; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mesenchymal stem cells; Mesenchymal stromal cells; Osteogenic differentiation; Adipogenic differentiation; Bone regeneration; Inflammation; Monocytes; Infection; Bacterial membrane vesicles; Compromised bone healing; Cell surface proteins; CD-markers; Osseointegration; Regenerative medicine;

    Abstract : Mesenchymal stem cells are multipotent stem cells with ability to differentiate into cells of the connective tissue lineage, such as adipocytes, osteoblasts and chondrocytes, both in vitro and in vivo. The main objective of the present thesis was to study different aspects of the osteogenic potential of MSCs. READ MORE

  5. 15. Bone Metabolism in Men

    Author : Peter Gillberg; Olof Johnell; Uppsala universitet; []
    Keywords : Medical sciences; Male osteoporosis; Bone mineral density; Growth hormone; Insulin-like growth factors; Sex hormones; Growth hormone replacement; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : In this thesis, the importance of the growth hormone (GH)/insulin-like growth factor (IGF) system and sex steroids for male bone metabolism has been investigated, and the effects of continuous low dose GH replacement in GH deficient (GHD) adults. In a population-based sample of men, positive correlations were found between bone mineral density (BMD) and IGF-I, IGF-II, IGF binding protein (IGFBP)-3 and the testosterone/sex hormone binding globulin (SHBG) ratio. READ MORE