Search for dissertations about: "Bone repair"
Showing result 1 - 5 of 64 swedish dissertations containing the words Bone repair.
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1. Survival of onlay bone grafts. A study in the adult rat
Abstract : The aim of this thesis was to study onlay bone grafting in the adult rat to improve graft incorporation and perservation of graft size. In 167 adult isogeneic lewis rats, the size maintenance and bone formation at the graft-host interface of uni- and bicortical onlays positioned in various environments and treatments were investigated. READ MORE
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2. Human embryonic stem cells for bone engineering applications
Abstract : The human skeleton represents the supporting structure of the organism and accounts for about 20 percent of the total body mass. Despite its intrinsic capacity to regenerate and self-repair, this ability is limited and repair therapies are needed in a large number of clinical cases. READ MORE
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3. Bone Enhancement with BMP-2 for Safe Clinical Translation
Abstract : Bone morphogenetic protein-2 (BMP-2) is considered a promising adjuvant for the treatment of bone regeneration. However, BMP-2 delivery in a conventional collagen scaffold needs a high dose to achieve an effective outcome. Moreover, such dosage may lead to serious side effects. READ MORE
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4. The Anabolic - Anti-catabolic Paradigm of Augmenting Skeletal Regeneration: A Bone Quality Perspective
Abstract : Successful fracture repair is a complex series of coordinated processes leading to regeneration of new bone to bridge the fracture site, remodelling of the newly formed bone and restoration of skeletal function. Disruption of these processes occurs in approximately 10% of all fractures and leads to delayed or failed healing requiring surgical interventions, increased complication rates, prolonged rehabilitation and high morbidity. READ MORE
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5. The effects of cyclosporin A on bone turnover and repair
Abstract : The effects of cyclosporin A on bone metabolism are unclear and controversial. The aims of this thesis were to study the effects of cyclosporin A on bone turnover and on different repair processes such as fracture healing, osteoinduction and osteoconduction. READ MORE