Search for dissertations about: "Botulinum"

Showing result 1 - 5 of 33 swedish dissertations containing the word Botulinum.

  2. 1. Botulinum neurotoxins

    Author : Sara Persson Košenina; Pål Stenmark; Rongsheng Jin; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; botulinum neurotoxins; biokemi; Biochemistry;

    Abstract : Botulinum neurotoxins (BoNTs) are the most potent toxins known to man, with less than 1 μg of pure toxin being enough to kill an adult man. Despite the high toxicity, BoNTs are widely used in cosmetics and in medicine for the treatment of an increasing number of medical conditions. READ MORE

  4. 2. Botulinum Toxin : Formulation, Concentration and Treatment

    Author : Alma Rystedt; Dag Nyholm; Carl Swartling; Klas Nordlind; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Botulinum toxin; Botox; Dysport; Xeomin; NeuroBloc; Hyperhidrosis; Cervical dystonia; Neurology; Neurologi;

    Abstract : Botulinum toxin (BTX) is used in various fields of medicine, including the treatment of hyperhidrosis and cervical dystonia. Botox®, Dysport®, Xeomin® and NeuroBloc® are commercially available BTX products, which are formulated differently and their dosing units are unique. READ MORE

  5. 3. Structural Insights into Botulinum Neurotoxins and the ALFA-tag System : Structural and Functional Studies of Proteins Related to the Botulinum Neurotoxins and Design of a Novel Epitope Tag

    Author : Markel Martínez-Carranza; Pål Stenmark; Thomas Binz; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; botulinum neurotoxin; Biochemistry; biokemi;

    Abstract : This thesis is divided into two sections; the first part describes our work in the field of botulinum neurotoxins (presented in papers I, II, III, and manuscript IV) and the second part summarizes our work involving the design of a new biochemical tool (presented in paper V).Botulinum neurotoxins (BoNTs) produced by the anaerobic bacterium Clostridium botulinum are the most poisonous substances known to date. READ MORE

  6. 4. Botulinum Toxin in the Treatment of Focal Hyperhidrosis and Dyshidrotic Hand Dermatitis

    Author : Carl Swartling; Klas Nordlind; Uppsala universitet; []
    Keywords : Medical sciences; Hyperhidrosis; dyshidrotic hand dermatitis; botulinum toxin; side-effects; EMG; quality of life; sweat glands; immunohistochemistry; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Dermatologi och venereologi; Dermatology and Venerology;

    Abstract : Excessive sweating may cause considerable disability, with psychological, social and occupational consequences. Primary hyperhidrosis may also play a key role in the pathogenesis of dyshidrotic dermatitis and some other skin diseases. READ MORE

  7. 5. Structural and functional studies of a novel Botulinum neurotoxin and of MTH1

    Author : Linda Henriksson; Pål Stenmark; Maria Selmer; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Botulinum neurotoxin; botulism; cancer; gene cluster; molecular structures; MTH1; NTNH; oxidised nucleotides; progenitor complex; protein expression; protein purification; X-ray crystallography; Biochemistry; biokemi;

    Abstract : X-ray crystallography visualizes the three dimensional molecular structures of proteins at atomic resolution. Seeing the molecular structure of a biomedically interesting protein enables a higher understanding of its function. READ MORE