Search for dissertations about: "Bradycardia"

Showing result 6 - 10 of 37 swedish dissertations containing the word Bradycardia.

  2. 6. Common mechanism for teratogenicity of antiepileptic drugs : Drug-induced embryonic arrhythmia and hypoxia-reoxygenation damage

    Author : Faranak Azarbayjani; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Atiepileptik drugs; embryonic heart; arrhythmia; cleft palate; ROS; antioxidants; Ikr; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; Toxicology; toxikologi;

    Abstract : The Antiepilptic drugs (AEDs) phenytoin (PHT), carbamazepine (CBZ), phenobarbital (PB), tri- and dimethadione (TMD and DMD) are known teratogens having a common malformation pattern in human and animal studies. This thesis was designed chiefly to test a hypothesis correlating the teratogenicity of these AEDs to episodes of pharmacologically induced embryonic arrhythmia and hypoxia-reoxygenation damage. READ MORE

  4. 7. Hypoxic Blackout in Serial Freediving – Protective Mechanisms and Risk Factors

    Author : Frank Pernett; Erika Schagatay; Glenn Björklund; Anton Westman; Mittuniversitetet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breath-hold diving; diving response; hyperventilation; hypoxia; oxygen saturation; oxygen stores; pulse oximetry; sonography; splenic contraction.;

    Abstract : Breath-hold diving or freediving exposes the body to stressors such as low oxygen and high carbon dioxide levels in the blood, increased hydrostatic pressure, and cold. The reduction in blood oxygen levels is considered a primary factor for loss of consciousness while diving. This is known as hypoxic blackout. READ MORE

  5. 8. Clonidine in pediatric anesthesia : aspects on population pharmacokinetics, nasal administration and safety

    Author : Peter Larsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Clonidine is widely use as premedication in pediatric patients and has many beneficial effects in the perioperative period. The introduction of population pharmacokinetics in the 1980s has proven useful when performing pharmacokinetic studies in children to circumvent previous limitations with traditional pharmacokinetics. READ MORE

  6. 9. Congenital heart block : a study of diagnostics, pathogenesis, prognosis and treatment

    Author : Håkan Eliasson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Congenital heart block (CHB) is a rare condition with considerable mortality. In most patients the disease is associated with fetal exposure to maternal SSA-Ro and/or SSB-La autoantibodies (AB) and develops in fetal life. Accuracy in fetal diagnostics is important to distinguish benign from life threatening conditions. READ MORE

  7. 10. Morbidity and mortality in patients with bundle branch block

    Author : Fariborz Tabrizi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : AV block; Bifascicular block; Congestive heart failure; Bundle branch block; Mortality; Myocardial infarction; Sudden cardiac death; Syncope.;

    Abstract : Background: Syncope is a predictor of subsequent high-degree atrioventricular (AV) block in patients with bifascicular block (BFB) but the time relationship between syncope and development of AV block has not been well-studied. Patients with BFB have a significantly higher mortality rate compared with an age and sex matched population. READ MORE