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Showing result 1 - 5 of 8 swedish dissertations matching the above criteria.

  2. 1. Cardiac surgery and the brain - studies on cerebral blood flow autoregulation and mechanisms of cerebral injury

    Author : Björn Reinsfelt; Göteborgs universitet; []
    Keywords : Cardiac surgery; cerrebral dysfunction; cardiopulmonary bypass; anaesthetics; aortic valve replacement; transcranial Doppler; cerebraospinal fluid; blood-brain barrier;

    Abstract : Cardiac surgery and the brain - studies on cerebral blood flow autoregulation and mechanisms of cerebral injury Björn Reinsfelt Department of Anaesthesiology and Intensive Care, Institute of Clinical Sciences, The Sahlgrenska Academy, University of Gothenburg, Sweden Abstract Cerebral dysfunction (CD) occurs frequently after cardiac surgery with cardiopulmonary bypass (CPB). The main causes of CD are thought to be cerebral hypoperfusion, cerebral microembolisation , cerebral inflammation or disruption of the blood brain barrier (BBB). READ MORE

  4. 2. Clinical Studies in the Acute Phase of Subarachnoid Haemorrhage

    Author : Maria Zetterling; Elisabeth Ronne Engström; Ola Nilsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Subarachnoid haemorrhage; microdialysis; brain energy metabolism; brain glucose; pyruvate; amino acids; cerebral oedema; ACTH; cortisol; Neurosurgery; Neurokirurgi; Neurosurgery; Neurokirurgi;

    Abstract : Patients admitted in similar clinical condition after spontaneous SAH can develop very different clinical courses. This could depend on the severity of the initial global ischemic brain injury at ictus. READ MORE

  5. 3. Mathematical Modelling of Cerebral Metabolism : From Ion Channels to Metabolic Fluxes

    Author : Nicolas Sundqvist; Gunnar Cedersund; Maria Engström; Roland Nilsson; Sebastian Sten; João Duarte; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The brain is the most metabolically active organ in the human body and therefore rely on a continuous supply of oxygen and glucose. Neuronal stimulation in specific regions of the leads to the firing of action potentials, a process facilitated by voltage-gated ion channels in the neurons’ cell membranes. READ MORE

  6. 4. Intrinsic and extrinsic protection of the brain

    Author : Peter Kimme; Olof Grände; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The brain is a complex organ and critically dependent on its oxygen metabolism and blood supply. The purpose of the present study was twofold: firstly to design, evaluate, and adopt a physiologically stable experimental model for repeated measurements of cerebral cortical microvascular perfusion by a new laser Doppler technique (experimental part (I) - intrinsic model). READ MORE

  7. 5. Cerebral blood flow and glucose metabolism in ischemic stroke : multimodal imaging investigations in a clinically relevant rat model

    Author : Fabian Arnberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Ischemic stroke is one of the leading causes of death worldwide. Ischemic stroke is also a major cause of long-term disability with vast socioeconomic results for patients, their relatives and health services. READ MORE