Search for dissertations about: "Brain infarct"
Showing result 1 - 5 of 36 swedish dissertations containing the words Brain infarct.
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1. Expression of TGF- isoforms, their receptors and related SMAD proteins in brain pathology : Immunohistochemical studies focusing on infarcts, abscesses and malignant gliomas
Abstract : This thesis focuses on the immunohistochemical expression of transforming growth factor beta(TGFβ) isoforms, their receptors and TGF-β-related SMAD proteins in brain pathology, chiefly in-farcts. One key question was whether the expressions of these compounds are altered within glial cells, endothelial cells of microvessels and other cell types in the vicinity of infarcts. READ MORE
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2. Apoptosis-related mechanisms in the immature brain after hypoxia-ischemia
Abstract : Aims: To characterize the activation of caspases-3 and extracellular signal-regulated kinase (ERK) in the neonatal brain after hypoxia-ischemia (HI) injury and evaluate the neuroprotective effect of X-linked inhibitor of apoptosis (XIAP) protein, erythropoietin (EPO) and the non-erythropoietic derivative asialoEPO. Methods: Seven-day-old rats or 9-day-old mice were subjected to HI. READ MORE
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3. Diffusion MRI of Small Ischemic Brain Lesions: Technical aspects, clinical experiences and diagnostic criteria
Abstract : Purpose: To compare the visualization of small ischemic brain lesions using diffusion using diffusion-weighted (DW) MRI and conventional imaging, with special regard to diagnostic efficiency. Imaging features of lesions of different ages, diagnostic limitations and technical principles were also investigated. READ MORE
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4. Inflammation and Cell Profileration Following Perinatal Brain Injury
Abstract : Inflammation plays an important role in cerebral ischemic injury in the immature brain. The aim of the thesis was to investigate (1) the role of astrocyte activation and reactive gliosis in neonatal hypoxic-ischemic (HI) brain injury, (2) the role of complement derived peptide C3a in neonatal HI brain injury, (3) the effect of neonatal HI brain injury on fear learning and behaviour, (4) the effects of lipopolysaccharide (LPS) induced systemic inflammation on cell proliferation in the developing brain. READ MORE
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5. Gene Expression Changes and Brain Plasticity after Experimental Stroke
Abstract : Stroke is the most common life-threatening neurological disease and ranks as the third leading cause of death in major industrialized countries. It is also the leading cause of serious long-term disability and about sixty percent of survivors have disabilities in their extremities. READ MORE