Search for dissertations about: "Brain parenchymal fraction"

Found 3 swedish dissertations containing the words Brain parenchymal fraction.

  2. 1. Brain parenchymal fraction in healthy individuals and in clinical follow-up of multiple sclerosis

    Author : Mattias Vågberg; Anders Svenningsson; Richard Birgander; Jonathan Gilthorpe; Anne-Marie Landtblom; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brain parenchymal fraction; Neurofilament light; Glial fibrillary acidic protein; Brain atrophy; Multiple Sclerosis; Clinical follow-up;

    Abstract : Background Multiple sclerosis (MS) is an autoimmune disease characterised by inflammatory damage to the central nervous system (CNS). Accumulated CNS injury can be quantified as brain atrophy, definable as a reduction in brain parenchymal fraction (BPF). BPF correlate with disability in MS and is used routinely as an endpoint in clinical trials. READ MORE

  4. 2. The Non-Invasive Brain Biopsy : Implementation and Application of Quantitative Magnetic Resonance Spectroscopy on Healthy and Diseased Human Brain

    Author : Anders Tisell; Peter Lundberg; Marcel Warntjes; Anne-Marie Landtblom; Örjan Smedby; Jan Weis; Linköpings universitet; []
    Keywords : ;

    Abstract : Introduction: In this thesis, one of the major objectives was to implement a method for (absolute) quantitative magnetic resonance spectroscopy (qMRS) of the human brain, intended for clinical use. The implemented method was based on standard spatially selective MRS sequences. READ MORE

  5. 3. Biomarkers in Multiple Sclerosis - Monitoring disease activity and treatment afficacy

    Author : Lenka Nováková Nyrén; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; biomarkers; multiple sclerosis; neurodegeneration; inflammation; treatment;

    Abstract : The pathophysiology of multiple sclerosis (MS) is complex with the presence of inflammation and neurodegeneration in all stages of the disease. The disease course, treatment response and outcome are highly variable in MS. READ MORE