Search for dissertations about: "Brain regions"

Showing result 1 - 5 of 412 swedish dissertations containing the words Brain regions.

  1. 1. Translational Aspects of Blood-Brain Barrier Transport and Brain Distribution of Drugs in Health and Disease

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Sofia Gustafsson; Uppsala universitet.; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Blood-brain barrier; Neurovascular unit; Pharmacokinetics; Neurodegenerative disease; Drug transport; Brain tissue binding; Positron emission tomography; Brain regions; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : A high unmet medical need in the area of CNS diseases coincides with high failure rates in CNS drug development. Efficient treatment of CNS disease is constrained by limited entrance of drugs into the brain owing to the blood-brain barrier (BBB), which separates brain from blood. READ MORE

  2. 2. Imaging brain aromatase by using PET A way to study anabolic steroid abuse

    University dissertation from Uppsala : Universitetsbiblioteket

    Author : Kayo Takahashi; Uppsala universitet.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; aromatase; brain; molecular imaging; PET; [11C]Vorozole; amygdala; hypothalamus; anabolic-androgenic steroids; abuse; [18F]Vorozole analogs; MEDICINE Morphology; cell biology; pathology Cell biology Neuroscience; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi Neurovetenskap;

    Abstract : Aromatase is an enzyme that facilitates the conversion of androgens to estrogens and may play a role in mood and mental status. The main theme of this thesis is the imaging of brain aromatase by use of the PET technique. The PET tracer for aromatase, 11C-labeled vorozole (VOZ) was developed and evaluated by with in vitro and in vivo methods. READ MORE

  3. 3. Human brain function evaluated with rCBF-SPECT memory and pain related changes and new diagnostic possibilities in Alzheimer’s disease

    University dissertation from Umeå : Umeå universitet

    Author : Torbjörn Sundström; Umeå universitet.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; brain imaging; rCBF; SPECT; early diagnosis; brain atlas; HMPAO; Alzheimer´s disease; Whiplash; neuropsychological function; episodic memory; MEDICINE Physiology and pharmacology Radiological research Diagnostic radiology; MEDICIN Fysiologi och farmakologi Radiologisk forskning Diagnostisk radiologi;

    Abstract : The aim of this doctoral thesis was to study the influence of memory, pain, age and education on the regional cerebral blood flow (rCBF), i.e. brain function, in early Alzheimer's disease (AD) and in chronic neck pain patients in comparison to healthy controls and in healthy elderly per se. READ MORE

  4. 4. Social Phobia. From Epidemiology to Brain Function

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Tomas Furmark; Uppsala universitet.; [2000]
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Psychology; Anxiety; brain; epidemiology; fear; neuroimaging; neurotransmitters; positron emission tomography; prevalence; serotonin; social phobia; subtypes; treatment; Psykologi; SOCIAL SCIENCES Social sciences Psychology; SAMHÄLLSVETENSKAP Socialvetenskap Psykologi; Psychology; psykologi;

    Abstract : Social phobia is a disabling anxiety disorder characterized by an excessive fear of negative evaluation in social situations. The present thesis explored the epidemiology and neurobiology of the disorder. By means of a mailed questionnaire, the point prevalence of social phobia in the Swedish general population was estimated at 15.6%. READ MORE

  5. 5. The conscious brain Empirical investigations of the neural correlates of perceptual awareness

    University dissertation from Umeå : Psykologi

    Author : Johan Eriksson; Umeå universitet.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; consciousness; visual perception; object identification; functional neuroimaging; top-down processing; prefrontal cortex; auditory perception; MEDICINE Morphology; cell biology; pathology Cell biology Neuroscience; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi Neurovetenskap;

    Abstract : Although consciousness has been studied since ancient time, how the brain implements consciousness is still considered a great mystery by most. This thesis investigates the neural correlates of consciousness by measuring brain activity with functional magnetic resonance imaging (fMRI) while specific contents of consciousness are defined and maintained in various experimental settings. READ MORE