Search for dissertations about: "Brain tumors"
Showing result 11 - 15 of 167 swedish dissertations containing the words Brain tumors.
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11. Metabolomics and proteomics studies of brain tumors : a chemometric bioinformatics approach
Abstract : The WHO classification of brain tumors is based on histological features and the aggressiveness of the tumor is classified from grade I to IV, where grade IV is the most aggressive. Today, the correlation between prognosis and tumor grade is the most important component in tumor classification. READ MORE
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12. Heparan Sulfate Proteoglycans in Brain Tumor Development
Abstract : Malignant brain tumors are aggressive neoplasms that remain challenging to treat in spite of their detailed molecular characterization. Both adults and children may suffer from brain tumors, which, if not lethal, can cause severe long-term and devastating side effects. READ MORE
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13. Genetic and Epigenetic Variation in the Human Genome : Analysis of Phenotypically Normal Individuals and Patients Affected with Brain Tumors
Abstract : Genetic and epigenetic variation is a key determinant of human diversity and has an impact on disease predisposition. Single nucleotide polymorphisms (SNPs) and copy number polymorphisms (CNPs) are the main forms of genetic variation. The challenge is to distinguish normal variations from disease-associated changes. READ MORE
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14. Experimental models of pediatric brain tumors. Establishment, immunophenotyping and clinical implications
Abstract : Brain tumors are the most common solid tumors in children. Current treatment protocols fail in 25% of patients and are associated with significant long-term adverse effects in survivors. READ MORE
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15. From Genes to Therapy : Modeling and Novel Therapeutic Strategies for Brain Tumors
Abstract : Medulloblastoma is the most common malignant pediatric brain tumor and is molecularly divided into four subgroups – WNT, SHH, Group 3 and Group 4. Two thirds of medulloblastoma patients survive, but survivors often suffer from severe, lifelong side-effects. The MYCN oncogene is deregulated in many medulloblastoma patients. READ MORE