Search for dissertations about: "Breast cancer in young females"

Found 5 swedish dissertations containing the words Breast cancer in young females.

  1. 1. Reproductive factors with respect to breast cancer risk and breast cancer survival

    Author : Mohammadhossein Hajiebrahimi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Breast cancer;

    Abstract : Aims: The primary aim of this thesis was to examine the potential relationship between indirect markers of exposure to hormones during pregnancy and the risk of and survival from breast cancer, with special emphasis on young patients. Our specific objectives were as follows: to determine whether the association between placental weight and offspring size, on the one hand, and maternal mortality from breast cancer, on the other, are influenced by tumor characteristics; to examine the association between birth weight and risk of breast cancer in the female member of opposite-sexed twins; and to investigate whether familial factors influence previously reported association between reproductive factors and risk of breast cancer. READ MORE

  2. 2. Autoimmune hepatitis in Sweden

    Author : Mårten Werner; Åke Danielsson; Ole Suhr; Per Stål; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Autoimmune hepatitis; epidemiology; cirrhosis; prognosis; thiopurines; pregnancy; breast feeding; relapse; hepatocellular cancer; lymphoma; Gastroenterology; Gastroenterologi; medicin; Medicine;

    Abstract : Autoimmune hepatitis (AIH) was identified as an entity by the Swedish professor Jan Waldenström in the 1950s. It was then denoted lupoid hepatitis, characterized by liver inflammation and most often affecting young women. READ MORE

  3. 3. Physiological and clinical studies of calcium-regulating hormones calcitonin and parathyroid hormone-related protein

    Author : Haiqin Rong; Karolinska Institutet; Karolinska Institutet; []
    Keywords : bone metabolism; breast cancer; calcitonin; calcium; exercise; lanthanide; milk; neonate; osteoporosis; parathyroid hormone-related protein; parturition; polymerase chain reaction; time-resolved fluorometry;

    Abstract : The present studies were performed to elucidate several physiological and clinical questions of calcitonin (CT) and parathyroid hormone-related protein (PTHrP) such as: a) Does age influence the basal and calcium-stimulated levels and circulating molecular forms of CT in healthy females? b) Are osteoporotic patients lacking circulating monomeric CT? c) How is salmon CT (sCT) absorbed and cleared during treatment of diseases? d) Is there any effect of acute physical activity on circulating CT, PTH, PTHrP and bone metabolic markers? e) Is there an absorbance of PTHrP in milk by the neonate? and f) Are there any interactions between CT and PTHrP? In addition, by use of time-resolved dissociation and enhancement lanthanide fluorometry, the effort was put to develop two-site immunofluorometric assays (IFMA) for sCT and PTHrP as well as a quantitative competitive PCR (QC-PCR) for measuring PTHrP mRNA and use these methods in some of the investigations. Heterogeneity of CT forms in serum was disclosed after immunoextraction, fast protein liquid chromatography (FPLC) and radioimmunoassay (RIA) in healthy females and osteoporotic patients. READ MORE

  4. 4. Patients with hyperprolactinemia clinical and epidemiological perspectives

    Author : Katarina Berinder; Karolinska Institutet; Karolinska Institutet; []
    Keywords : prolactin;

    Abstract : Hyperprolactinemia (HPL) is the most common endocrine disorder of the hypothalamic- pituitary axis and prolactinomas the most frequent pituitary tumour. A majority of the patients are women in reproductive age seeking health care for menstrual disorders or infertility. READ MORE

  5. 5. Ewing sarcoma : treatment, prognosis and late effects

    Author : Asle Charles Hesla; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Ewing sarcoma (ES) is a rare and aggressive childhood/adolescent malignancy which relies on a multidisciplinary treatment approach for cure. The overall survival rate for this young patient group has hardly improved over the last 30 years despite large multinational treatment trials. READ MORE