Search for dissertations about: "Bromodeoxyuridine"

Showing result 16 - 19 of 19 swedish dissertations containing the word Bromodeoxyuridine.

2. 16. Studies on mechanisms in liver fibrosis

   Author : Nils Kinnman; Karolinska Institutet; Karolinska Institutet; []
   Keywords : bile duct epithelial cell; chernotaxis; cholestasis; cystic fibrosis; cystic fibrosis transmembrane conductance regulator; endothelin; hepatic stellate cell; hepatitis C virus; liver fibrosis; platelet-derived growth factor; platelet-derived growth factor receptor [beta]; smooth muscle [alpha]-actin; transforming growth factor- [beta]; tumor necrosis factor-[alpha];

   Abstract : The aim of the present study was to elucidate mechanisms involved in liver fibrogenesis, the wound healing response of the liver to chronic injury. A role for TNF-[alpha] and all three isoforms of TGF-[beta] in the pathogenesis of hepatitis C related liver disease was suggested by the finding of increased expression of TGF-[beta]1-3, latent TGF-[beta] binding protein (LTBP), and TNF-[alpha] by immunohistochemistry in areas of inflammation and fibrosis in liver tissue from untreated patients with hepatitis C. READ MORE

4. 17. Reverse transcriptase assay for analysis of resistance to anti-HIV drugs and their mechanism of action

   Author : Xingwu Shao; Karolinska Institutet; Karolinska Institutet; []
   Keywords : HIV-1; RT; antiviral drugs; NRTls; NNRTls; drug resistance; viral load;

   Abstract : Reverse transcriptase (RT) is a viral enzyme and one of the main targets for drugs against human immunodeficiency virus (HIV). This work presents a set of sensitive non-radioactive RT assays were developed: standard RT inhibition assay (IC assay); RT binding inhibition assay; RTprotein detection assay and template-primer destruction assay or chain termination assay (CT assay). READ MORE

5. 18. Allergic airway inflammation and bone marrow eosinophilopoiesis. Modulation by cytokines

   Author : Lin-Ling Zhao; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allergy; airway inflammation; cytokine; eosinophil; eosinophilopoiesis;

   Abstract : Accumulation of eosinophils in the airways and lung parenchyma is one of the hallmarks of allergic airway inflammation. This cellular inflammatory response is likely to involve the release of eosinophils from peripheral storage pools and possibly cause production of eosinophils in the bone marrow (BM). READ MORE

6. 19. New neurons and astrocytes in the adult brain. Studies on adult rat neural progenitors in vivo and in vitro with special reference to the effects of IGF-I and CNTF regarding proliferation and lineage determination

   Author : Maria A I Åberg; Göteborgs universitet; []
   Keywords : Brain; hippocampus; rat; neurogenesis; progenitor cell; stem cell; ciliary neurotrophic factor; insulin-like growth factor-I; PI3-K; MAPK.;

   Abstract : The hippocampal dentate gyrus in several species, including man, continues to produce new neurons and glial cells in adulthood. The generation of new neurons and glial cells in the adult hippocampus is under strict regulation. Two major events of significance for cell genesis from progenitor cells are proliferation and lineage determination. READ MORE