Search for dissertations about: "Burkitt Iymphoma"

Found 3 swedish dissertations containing the words Burkitt Iymphoma.

  1. 1. p53 inactivation by point mutations and splice site mutations in human and mouse tumors

    University dissertation from Stockholm : Karolinska Institutet, false

    Author : Kristinn P. Magnússon; Karolinska Institutet.; Karolinska Institutet.; [1998]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; p53; Burkitt Iymphoma; apoptosis; alternative splicing; mutation; ascites;

    Abstract : The p53 tumor suppressor gene is frequently mutated in human tumors. p53 induces cell cycle arrest and/or apoptosis in response to cellular stress, such as DNA damage, hypoxia and certain activated oncogenes like c-myc. The status of p53 in Burkitt's Iymphoma (BL) cell lines was investigated. The majority of BL lines expressed mutated p53 protein. READ MORE

  2. 2. Characteristics of EBV-infected B cell lines and B-CLL clones which determine their interaction with lymphocytes

    University dissertation from Stockholm : Karolinska Institutet, false

    Author : Javier Federico Avila-Carino; Karolinska Institutet.; Karolinska Institutet.; [1997]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; EBV; Burkitt Iymphoma; CLL; MLC; antiviral response phenotype; cytokines.;

    Abstract : CHARACTERISTICS OF EBV-INFECTED B CELL LINES AND B-CLL CLONES WHICH DETERMINE THEIR INTERACTION WITH T LYMPHOCYTES Javier Federico Avila-Cariho Doctoral dissertation from the Microbiology and Tumor Biology Center, Karolinska Institutet, Stockholm, Sweden The results concerning T Iymphocyte mediated recognition of Epstein-Barr virus (EBV) carrying Burkitt Iymphoma (BL) cell lines and EBV-infected chronic Iymphocytic leukemia (CLL) B cells contribute to the understanding of the generally harmless host-EBV interaction and may be extrapolated to the fate of normal B cells after EBV infection. The phenotype of EBV negative BL lines resembles resting B cells. READ MORE

  3. 3. Murine plasmacytomagenesis : An experimental model of B-cell neoplasia

    University dissertation from Stockholm : Karolinska Institutet, false

    Author : Santiago C Silva; Karolinska Institutet.; Karolinska Institutet.; [1997]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mouse plasmacytomas; chromosomal translocation; chimeric mice; MYC-transgenic mice; ;

    Abstract : MURINE PLASMACYTOMAGENESIS: AN EXPERIMENTAL MODEL OF B-CELL NEOPLASIA Santiago Silva C Microbiology and Tumorbiology Center (MTC) Karolinska Institute, S-171 77 Stockholm A chromosomal translocation which results in the illegitimate activation of the c-myc proto-oncogene by one of the three immunoglobulin (Ig) loci is invariably associated with human Burkitt's Iymphoma (BL), mouse plasmacytoma (MPC) and rat immunocytomas (RIC). In the MPC system a genetic predisposition linked to the BALB/c strain has been suggested. READ MORE