Search for dissertations about: "Burkitt Iymphoma"

Found 2 swedish dissertations containing the words Burkitt Iymphoma.

2. 1. p53 inactivation by point mutations and splice site mutations in human and mouse tumors

   Author : Kristinn P Magnússon; Karolinska Institutet; Karolinska Institutet; []
   Keywords : p53; Burkitt Iymphoma; apoptosis; alternative splicing; mutation; ascites;

   Abstract : The p53 tumor suppressor gene is frequently mutated in human tumors. p53 induces cell cycle arrest and/or apoptosis in response to cellular stress, such as DNA damage, hypoxia and certain activated oncogenes like c-myc. The status of p53 in Burkitt's Iymphoma (BL) cell lines was investigated. The majority of BL lines expressed mutated p53 protein. READ MORE

4. 2. Characteristics of EBV-infected B cell lines and B-CLL clones which determine their interaction with lymphocytes

   Author : Javier Federico Avila-Carino; Karolinska Institutet; Karolinska Institutet; []
   Keywords : EBV; Burkitt Iymphoma; CLL; MLC; antiviral response phenotype; cytokines.;

   Abstract : The results concerning T Iymphocyte mediated recognition of Epstein-Barr virus (EBV) carrying Burkitt Iymphoma (BL) cell lines and EBV-infected chronic Iymphocytic leukemia (CLL) B cells contribute to the understanding of the generally harmless host-EBV interaction and may be extrapolated to the fate of normal B cells after EBV infection. The phenotype of EBV negative BL lines resembles resting B cells. READ MORE