Search for dissertations about: "C EBP transcription factors"
Showing result 11 - 15 of 17 swedish dissertations containing the words C EBP transcription factors.
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11. Transcriptional regulation of the Epstein-Barr virus nuclear antigen 1 gene in latent and lytic stages of infection
Abstract : Epstein-Barr virus (EBV) is a lymphotropic herpesvirus that infects more than 90% of humans worldwide. The virus is the causative agent of infectious mononucleosis, a self-limiting lymphoproliferative disorder, and is also associated with a variety of malignancies including Burkitt's lymphoma (BL), Hodgkin's disease (HD), nasopharyngeal carcinoma (NPC), and lymphoproliferative disorders in immunocompromised individuals. READ MORE
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12. Transcriptional control of Bactericidal/permeability increasing protein (BPI) and cathepsin G in myeloid cells
Abstract : The neutrophil store its effector proteins in several distinct types of cytoplasmic granules, developed sequentially during cell maturation. The different subtypes of granules have unique protein content and functional characteristics. The formation of each granule subtype coincides with the biosynthesis of its content. READ MORE
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13. The Role of Stat1 in Retinoic Acid-induced Myelomonocytic Differentiation of Human Leukemia Cells
Abstract : All-trans retinoic acid (ATRA), a biologically active metabolite of vitamin A, is a powerful inducer of terminal differentiation and growth arrest of several myeloid cell lines in vitro. Although the efficacy of ATRA as an anti-cancer drug has been demonstrated by the successful treatment of acute promyelocytic leukemia (APL), knowledge concerning the molecular mechanisms directing ATRA-induced differentiation and cell cycle arrest of myeloid cells is lacking. READ MORE
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14. Bactericidal/Permeability-Increasing Protein (BPI) and Proteinase 3: Studies at the Transcriptional Level
Abstract : In myelopoiesis, neutrophils and monocytes/macrophages are formed from a common myeloid precursor cell in the bone marow. During maturation of neutrophils, cytoplasmic granules are formed in the cells and the content of these granules is critical for the function of neutrophils in the first line of defense against invading microorganisms. READ MORE
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15. Molecular studies of genetic changes in myxoid and round cell liposarcoma
Abstract : Chromosomal translocations commonly result in the production of fusion genes and the fusion genes are often tumor-type specific. In myxoid and round cell liposarcomas (MLS/RCLS), almost 95% of the cases carry a t(12;16)(q13;p11). In the remaining 5% of the MLS/RCLS tumors, another translocation and fusion gene can be found, i.e. READ MORE