Search for dissertations about: "C-EBPbeta"

Found 5 swedish dissertations containing the word C-EBPbeta.

  2. 1. Regulation of mucosal inflammation by fibroblasts

    Author : Tanya (De L.) Karlson; Göteborgs universitet; []
    Keywords : inflammatory bowel diseases; fibroblasts; CD40; C-EBPbeta; apoptosis; TGF-beta;

    Abstract : ABSTRACT Acute inflammation in the bowel, a response of the immune system to infections or trauma, is probably a frequent but localized event, but when the barrier is repaired and the infection cleared, it is quickly followed by wound healing and resolution. However, in some individuals these mechanisms are not effective and the inflammatory bowel diseases, Crohn?s disease and ulcerative colitis result. READ MORE

  4. 2. C/EBP transcription factors in lung cellular differentiation and development

    Author : Tove Berg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : C EBP transcription factors; lung; development; differentiation; glucocorticoid regulation;

    Abstract : During embryonic development the lung is lined with a primitive epithelium. As development proceeds, the epithelium matures and differentiates into several cell types that together with cells of mesenchymal origin constitute the adult lung. READ MORE

  5. 3. Intracellular signaling in the lung : a role for C/EBP transcription factors in chronic obstructive pulmonary disease, glucocorticoid signaling and lung development

    Author : Lukas Didon; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Over the last decade, a previously unknown role has been established for members of the C/EBP transcription factor family in lung gene expression. In other organs, C/EBPs are well known regulators of cell differentiation and linked processes such as proliferation, apoptosis, gene expression as well as central regulators of inflammatory responses and infectious defenses. READ MORE

  6. 4. Fatty acids induce potentially atherogenic changes in extracellular matrix proteoglycans

    Author : Mariam Rodríguez-Lee; Göteborgs universitet; []
    Keywords : proteoglycans; glycosaminoglycans; fatty acids; smooth muscle cells; hepatocytes; LDL binding; remnant clearance; insulin resistance; type 2 diabetes;

    Abstract : Insulin resistance and type 2 diabetes (T2D) are associated with an increased prevalence of atherosclerotic cardiovascular disease (CVD). A key step in the initiation of atherogenesis is retention of low density lipoproteins (LDL) in the intima by chondroitin sulfate (CS)-rich proteoglycans (PG). READ MORE

  7. 5. Studies on function and regulation of the transcription factor C/EBPalpha

    Author : Per Flodby; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The transcription factor C/EBPalpha was originally identified as a protein involved in hepatocyte-specific gene regulation. Later, it has been demonstrated that C/EBPalpha is expressed in several other tissues, mainly in adipose cells, lung, intestine, skin and in myeloid cells. READ MORE