Search for dissertations about: "C. Carlsson"

Showing result 16 - 20 of 51 swedish dissertations containing the words C. Carlsson.

  2. 16. Nuclear hormone receptors studied by molecular dynamics computer simulations

    Author : Peter Carlsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Nuclear hormone receptor; glucocorticoid; molecular dynamics; simulation; ligand; coactivator; protein; solvation;

    Abstract : Nuclear hormone receptors form a super family of homologous transcription factors. The liganddependent nuclear receptors are important drug targets controlling metabolic and inflammatory disorders, amongst others. READ MORE

  4. 17. Peripheral immunity in patients with autoimmune endocrine diseases and the influence of physiological adaptions during pregnancy

    Author : Louise Magnusson; Per-Ola Carlsson; Rosaura Casas; Ola Winqvist; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; Hashimoto´s thyroiditis; Graves´ disease; autoimmune Addison´s disease; antigen-presenting cells; B cells; non-classical monocytes; NK cells; memory CD8 T cells; CDCP1; SLAMF1; inflammation; lymphocyte activation; pregnancy; β-cell function; C-peptide; plasma proteome; prolactin; prokineticin-1; glucagon; oral glucose tolerance test; mass cytometry; proximity extension assay; Medicinsk vetenskap; Medical Science; Klinisk immunologi; Clinical Immunology; Endocrinology and Diabetology; Endokrinologi och Diabetologi; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Abstract : Type 1 diabetes (T1D), Hashimoto’s thyroiditis (HT), Graves’ disease (GD), and autoimmune Addison’s disease (AD) appear to share immunogenetic mechanisms. This idea is not novel, as “autoimmune tautology” is an established concept. READ MORE

  5. 18. The importance of psychological and physical stressors on diabetes-related immunity in a young population – an interdisciplinary approach

    Author : Emma Carlsson; Maria Faresjö; Arne Gerdner; Anneli Frostell; Kristina Lejon; Jönköping University; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; psychological stressors; physical stressors; cellular immune system; type 1 diabetes; young population;

    Abstract : Background: The prevalence of immunological disorders such as type 1 diabetes (T1D) is increasingly common amongst children, adolescents and young adults. There is also an increase in psychosomatic symptoms (depression, insomnia, anxiety, headaches and fatigue etc. READ MORE

  6. 19. Kostmann syndrome : a clinical and pathophysiological study

    Author : Göran Carlsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Kostmann syndrome; severe congenital neutropenia; autosomal recessive; periodontitis; antibacterial peptides; LL-3 7; apoptosis; Bcl-2; granulocyte colony-stimulating factor; glycosylation; lenograstim; filgrastim.;

    Abstract : Kostmann syndrome or severe congenital neutropenia (SCN) is a rare disease, usually diagnosed during the first months of life, characterized by extremely low levels of neutrophils in the peripheral blood, a maturational arrest of the myelopoiesis in the bone marrow and severe bacterial infections. The purpose of this project was to improve the understanding of the clinical course and the pathophysiology of autosomal recessive SCN. READ MORE

  7. 20. Surface Stabilization and Electrochemical Properties from a Theoretical Perspective

    Author : Daniel Petrini; Karin Larsson; Jan-Otto Carlsson; Martin Stutzmann; Uppsala universitet; []
    Keywords : Inorganic chemistry; DFT; Diamond; High surface conductivity; Surface reactivity; c-BN; Oorganisk kemi;

    Abstract : Diamond and cubic boron nitride surfaces have extreme properties that can be exploited in novel tribological, electrochemical and electronic applications. Normally insulating diamond surfaces can exhibit high surface conductivities due to hydrogen termination and the nature of the surrounding atmosphere. READ MORE