Search for dissertations about: "C. Lundström"

Showing result 1 - 5 of 17 swedish dissertations containing the words C. Lundström.

  2. 1. Clearing up Culex Confusion : A Basis for Virus Vector Discrimination in Europe

    Author : Jenny C. Hesson; Jan O. Lundström; Örjan Östman; Åke Lundkvist; Anssi Laurila; Laura D Kramer; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Culex torrentium; Culex pipiens; mosquitoes; vector; ornithophilic; Sindbis virus; West Nile virus; Populationsbiologi; Population Biology;

    Abstract : Mosquito species of the Culex genus are the enzootic vectors for several bird-associated viruses that cause disease in humans. In Europe, these viruses include Sindbis (SINV), West Nile and Usutu viruses. The morphologically similar females of Cx. torrentium and Cx. READ MORE

  4. 2. Structural biology of transcriptional regulation in the c-Myc network

    Author : Sara Helander; Maria Sunnerhagen; Patrik Lundström; Lila M. Gierasch; Linköpings universitet; []
    Keywords : ;

    Abstract : The oncogene c-­‐Myc is overexpressed in many types of human cancers and regulation of c-­‐Myc expression is crucial in a normal cell. The intrinsically disordered N-­‐terminal transactivation domain interacts with a wide range of proteins regulating c-­‐Myc activity. READ MORE

  5. 3. From genetic associations to biological implications in multiple sclerosis

    Author : Wangko Lundström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Every year, 600 people in Sweden develop MS, making it the second most common cause of disability (after accidents) in young adults. The pathophysiology is characterized by inflammation of the central nervous system and impaired neuronal signaling. READ MORE

  6. 4. Protein Dynamics Studied by NMR Spin Relaxation. Conformational Transitions of a Calmodulin Mutant

    Author : Patrik Lundström; Biofysikalisk kemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molekylär biofysik; Molecular biophysics; spin relaxation; rotating-frame; NMR; multiple-quantum; EF-hand; chemical shift; chemical exchange; calcium binding proteins; calmodulin;

    Abstract : Binding of calcium to the protein calmodulin leads to molecular reorganization that enables interaction with target peptides and activation of downstream processes. I have studied the dynamics of the calcium-loaded form of a C-terminal calmodulin mutant (E140Q-Tr2C) using NMR spin relaxation experiments. READ MORE

  7. 5. Corticosteroids in advanced cancer : epidemiology, symptom relief and patient experiences

    Author : Staffan Lundström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Corticosteroids; cancer; palliative care; anorexia; nausea; symptom assessment; existential;

    Abstract : Cortisol is the principal circulating glucocorticoid in man and has a wide variety of effects in the body. In advanced metastatic cancer, glucocorticoids are used to alleviate symptoms such as anorexia, poor strength and poor wellbeing. The mechanisms behind the symptom relieving effects are still unclear. READ MORE